Unreviewed, UniProtKB/TrEMBL A5A1E8 (A5A1E8_RAT)

Names and origin

Protein names

Submitted name:
    Frizzled 8 EMBL ABP57805.1

Gene names

Name:

Fz8 EMBL ABP57805.1

Organism

Rattus norvegicus (Rat) EMBL ABP57805.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	109 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 FZ (frizzled) domain. Spearmint SPM017981

Ontologies

Keywords
Biological process	Wnt signaling pathway Spearmint SPM017981
Cellular component	Membrane
Domain	Transmembrane Spearmint SPM015526
Molecular function	Developmental protein Spearmint SPM017981 G-protein coupled receptor Spearmint SPM015526 Receptor Transducer
Gene Ontology (GO)
Biological process	G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW Wnt receptor activity Inferred from electronic annotation. Source: Compara Wnt-protein binding Inferred from electronic annotation. Source: Compara non-G-protein coupled 7TM receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL ABP57805.1
	Non-terminal residue	109	1	EMBL ABP57805.1

Sequences

	Sequence		Length	Mass (Da)
	A5A1E8-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: F89A04F01FE993ED	FASTA	109	12,635
	10 20 30 40 50 60 PLVIYLFIGT MFLLAGFVSL FRIRSVIKQQ GGPTKTHKLE KLMIRLGLFT VLYTVPAAVV 70 80 90 100 VACLFYEQHN RPRWEATHNC PCLRDLQPDQ ARRPDYAVFM LKYFMCLVV

References

[1]	"Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells." Kordes C., Sawitza I., Haussinger D. Biochem. Biophys. Res. Commun. 367:116-123(2008) [PubMed: 18158920] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Wistar EMBL ABP57805.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	EF519320 mRNA. Translation: ABP57805.1.
IPI	IPI00360182.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5A1E8.
Genome annotation databases
Ensembl	ENSRNOT00000058837; ENSRNOP00000055627; ENSRNOG00000038571; Rattus norvegicus. [Genome view]
Gene expression databases
Genevestigator	A5A1E8.
Family and domain databases
InterPro	IPR000539. Frizzled. IPR015526. Frizzled_related. IPR017981. GPCR_2-like. [Graphical view]
PANTHER	PTHR11309. Fz_related. 1 hit.
Pfam	PF01534. Frizzled. 1 hit. [Graphical view]
PRINTS	PR00489. FRIZZLED.
PROSITE	PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5A1E8_RAT

Accession

Primary (citable) accession number: A5A1E8

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)