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Protein

Solute carrier family 2, facilitated glucose transporter member 7

Gene

Slc2a7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei331MonosaccharideBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 7
Alternative name(s):
Glucose transporter type 7
Short name:
GLUT-7
Gene namesi
Name:Slc2a7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1583902. Slc2a7.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21CytoplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Topological domaini43 – 78ExtracellularSequence analysisAdd BLAST36
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 107CytoplasmicSequence analysis8
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Topological domaini129 – 138ExtracellularSequence analysis10
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Topological domaini160 – 172CytoplasmicSequence analysisAdd BLAST13
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 198ExtracellularSequence analysis5
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Topological domaini220 – 281CytoplasmicSequence analysisAdd BLAST62
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Topological domaini303 – 321ExtracellularSequence analysisAdd BLAST19
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21
Topological domaini343 – 350CytoplasmicSequence analysis8
Transmembranei351 – 371HelicalSequence analysisAdd BLAST21
Topological domaini372 – 379ExtracellularSequence analysis8
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Topological domaini401 – 415CytoplasmicSequence analysisAdd BLAST15
Transmembranei416 – 436HelicalSequence analysisAdd BLAST21
Topological domaini437 – 445ExtracellularSequence analysis9
Transmembranei446 – 466HelicalSequence analysisAdd BLAST21
Topological domaini467 – 512CytoplasmicSequence analysisAdd BLAST46

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172731 – 512Solute carrier family 2, facilitated glucose transporter member 7Add BLAST512

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi57N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliA4ZYQ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni294 – 300Monosaccharide bindingBy similarity7

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG014816.
InParanoidiA4ZYQ5.
KOiK12201.
PhylomeDBiA4ZYQ5.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4ZYQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKEAGTPP PIPSREGRLQ PTLLLATLSA AFGSAFQYGY NLSVVNTPHK
60 70 80 90 100
VFKSFYNETY FERHATFMDG KLMLLLWSCT VSMFPLGGLL GSLLVGLLVD
110 120 130 140 150
SCGRKGTLLI NNIFAIIPAI LMGVSKVAKA FELIVFSRVV LGVCAGISYS
160 170 180 190 200
ALPMYLGELA PKNLRGMVGT VTEVFVIVGV FLAQIFSLQA ILGNPAGWPV
210 220 230 240 250
LLALTGVPAL LQLLTLPFFP ESPRYSLIQK GDEATARQAL RRLRGHTDME
260 270 280 290 300
AELEDMRAEA RAERAEGHLS VLHLCALRSL RWQLLSIIVL MAGQQLSGIN
310 320 330 340 350
AVNYYADTIY TSAGVEAAHS QYVTVGSGVV NIVMTITSAV LVERLGRRHL
360 370 380 390 400
LLAGYGICGS ACLVLTVVLL FQNRVPELSY LGIICVFAYI AGHSIGPSPV
410 420 430 440 450
PPVVRTEIFL QSSRRAAFMV DGAVHWLTNF IIGFLFPSIQ EAIGAYSFII
460 470 480 490 500
FAGICLLTAI YIYVVIPETK GKTFVEINRI FAKRNRVKLP EEKEETIDAG
510
PPTASPAKET SF
Length:512
Mass (Da):55,691
Last modified:May 29, 2007 - v1
Checksum:iE40861624BFB18E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF501821 mRNA. Translation: ABP68403.1.
RefSeqiNP_001094490.1. NM_001101020.1.
UniGeneiRn.217486.

Genome annotation databases

GeneIDi100362644.
KEGGirno:100362644.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF501821 mRNA. Translation: ABP68403.1.
RefSeqiNP_001094490.1. NM_001101020.1.
UniGeneiRn.217486.

3D structure databases

ProteinModelPortaliA4ZYQ5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100362644.
KEGGirno:100362644.

Organism-specific databases

CTDi155184.
RGDi1583902. Slc2a7.

Phylogenomic databases

HOVERGENiHBG014816.
InParanoidiA4ZYQ5.
KOiK12201.
PhylomeDBiA4ZYQ5.

Miscellaneous databases

PROiA4ZYQ5.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGTR7_RAT
AccessioniPrimary (citable) accession number: A4ZYQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: November 30, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.