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Protein
Submitted name:

Arylamine N-acetyltransferase 2

Gene

NAT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. acetyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Arylamine N-acetyltransferase 2Imported
Gene namesi
Name:NAT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Structurei

3D structure databases

ProteinModelPortaliA4Z7J7.
SMRiA4Z7J7. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arylamine N-acetyltransferase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG000165.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.

Sequencei

Sequence statusi: Complete.

A4Z7J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL
60 70 80 90 100
GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK
110 120 130 140 150
YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF
160 170 180 190 200
CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
210 220 230 240 250
DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT
260 270 280 290
DLVEFKTLTE EEVEEVLRNI FKISLGRNLV PKPGDESLTI
Length:290
Mass (Da):33,643
Last modified:May 29, 2007 - v1
Checksum:iFAEE3BC2131F000E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ472998 Genomic DNA. Translation: ABF01396.1.
DQ473160 Genomic DNA. Translation: ABF01558.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ472998 Genomic DNA. Translation: ABF01396.1.
DQ473160 Genomic DNA. Translation: ABF01558.1.

3D structure databases

ProteinModelPortaliA4Z7J7.
SMRiA4Z7J7. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG000165.

Miscellaneous databases

NextBioi35461956.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.
ProtoNetiSearch...

Publicationsi

  1. "Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene."
    Patin E., Harmant C., Quintana-Murci L.
    Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CHAGGA4152-1Imported and SAN1029-1Imported.

Entry informationi

Entry nameiA4Z7J7_HUMAN
AccessioniPrimary (citable) accession number: A4Z7J7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: October 1, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.