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Protein
Submitted name:

Arylamine N-acetyltransferase 2

Gene

NAT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Arylamine N-acetyltransferase 2Imported
Gene namesi
Name:NAT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA18.

Expressioni

Gene expression databases

BgeeiA4Z6T7.
ExpressionAtlasiA4Z6T7. baseline and differential.
GenevisibleiA4Z6T7. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000286479.

Structurei

3D structure databases

ProteinModelPortaliA4Z6T7.
SMRiA4Z6T7. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arylamine N-acetyltransferase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000012054.
HOVERGENiHBG000165.
KOiK00622.
OMAiDHIVRRN.
PhylomeDBiA4Z6T7.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.

Sequencei

Sequence statusi: Complete.

A4Z6T7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL
60 70 80 90 100
GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK
110 120 130 140 150
YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF
160 170 180 190 200
CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
210 220 230 240 250
DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT
260 270 280 290
DLVEFKTLTE EEVEEVLRNI FKISLGRNLV PKPGDGSLTI
Length:290
Mass (Da):33,571
Last modified:May 29, 2007 - v1
Checksum:iFAEE3BC2107F000E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ472738 Genomic DNA. Translation: ABF01136.1.
DQ472742 Genomic DNA. Translation: ABF01140.1.
DQ472746 Genomic DNA. Translation: ABF01144.1.
DQ472749 Genomic DNA. Translation: ABF01147.1.
DQ472754 Genomic DNA. Translation: ABF01152.1.
DQ472755 Genomic DNA. Translation: ABF01153.1.
DQ472768 Genomic DNA. Translation: ABF01166.1.
DQ472778 Genomic DNA. Translation: ABF01176.1.
DQ472793 Genomic DNA. Translation: ABF01191.1.
DQ472796 Genomic DNA. Translation: ABF01194.1.
DQ472798 Genomic DNA. Translation: ABF01196.1.
DQ472804 Genomic DNA. Translation: ABF01202.1.
DQ472808 Genomic DNA. Translation: ABF01206.1.
DQ472812 Genomic DNA. Translation: ABF01210.1.
DQ472813 Genomic DNA. Translation: ABF01211.1.
DQ472816 Genomic DNA. Translation: ABF01214.1.
DQ472820 Genomic DNA. Translation: ABF01218.1.
DQ472832 Genomic DNA. Translation: ABF01230.1.
DQ472864 Genomic DNA. Translation: ABF01262.1.
DQ472868 Genomic DNA. Translation: ABF01266.1.
DQ472869 Genomic DNA. Translation: ABF01267.1.
DQ472873 Genomic DNA. Translation: ABF01271.1.
DQ472881 Genomic DNA. Translation: ABF01279.1.
DQ472892 Genomic DNA. Translation: ABF01290.1.
DQ472906 Genomic DNA. Translation: ABF01304.1.
DQ472914 Genomic DNA. Translation: ABF01312.1.
DQ472929 Genomic DNA. Translation: ABF01327.1.
DQ472941 Genomic DNA. Translation: ABF01339.1.
DQ472949 Genomic DNA. Translation: ABF01347.1.
DQ472951 Genomic DNA. Translation: ABF01349.1.
DQ472952 Genomic DNA. Translation: ABF01350.1.
DQ472961 Genomic DNA. Translation: ABF01359.1.
DQ472964 Genomic DNA. Translation: ABF01362.1.
DQ472980 Genomic DNA. Translation: ABF01378.1.
DQ472996 Genomic DNA. Translation: ABF01394.1.
DQ473006 Genomic DNA. Translation: ABF01404.1.
DQ473012 Genomic DNA. Translation: ABF01410.1.
DQ473015 Genomic DNA. Translation: ABF01413.1.
DQ473016 Genomic DNA. Translation: ABF01414.1.
DQ473026 Genomic DNA. Translation: ABF01424.1.
DQ473027 Genomic DNA. Translation: ABF01425.1.
DQ473030 Genomic DNA. Translation: ABF01428.1.
DQ473031 Genomic DNA. Translation: ABF01429.1.
DQ473034 Genomic DNA. Translation: ABF01432.1.
DQ473039 Genomic DNA. Translation: ABF01437.1.
DQ473044 Genomic DNA. Translation: ABF01442.1.
DQ473095 Genomic DNA. Translation: ABF01493.1.
DQ473107 Genomic DNA. Translation: ABF01505.1.
DQ473111 Genomic DNA. Translation: ABF01509.1.
DQ473112 Genomic DNA. Translation: ABF01510.1.
DQ473113 Genomic DNA. Translation: ABF01511.1.
DQ473114 Genomic DNA. Translation: ABF01512.1.
DQ473115 Genomic DNA. Translation: ABF01513.1.
DQ473130 Genomic DNA. Translation: ABF01528.1.
DQ473134 Genomic DNA. Translation: ABF01532.1.
DQ473136 Genomic DNA. Translation: ABF01534.1.
DQ473139 Genomic DNA. Translation: ABF01537.1.
DQ473143 Genomic DNA. Translation: ABF01541.1.
DQ473144 Genomic DNA. Translation: ABF01542.1.
DQ473146 Genomic DNA. Translation: ABF01544.1.
DQ473149 Genomic DNA. Translation: ABF01547.1.
DQ473152 Genomic DNA. Translation: ABF01550.1.
DQ473153 Genomic DNA. Translation: ABF01551.1.
DQ473154 Genomic DNA. Translation: ABF01552.1.
DQ473155 Genomic DNA. Translation: ABF01553.1.
DQ473159 Genomic DNA. Translation: ABF01557.1.
DQ473163 Genomic DNA. Translation: ABF01561.1.
DQ473187 Genomic DNA. Translation: ABF01585.1.
DQ473208 Genomic DNA. Translation: ABF01606.1.
DQ473212 Genomic DNA. Translation: ABF01610.1.
DQ473213 Genomic DNA. Translation: ABF01611.1.
DQ473216 Genomic DNA. Translation: ABF01614.1.
DQ473217 Genomic DNA. Translation: ABF01615.1.
DQ473219 Genomic DNA. Translation: ABF01617.1.
DQ473230 Genomic DNA. Translation: ABF01628.1.
DQ473233 Genomic DNA. Translation: ABF01631.1.
DQ473235 Genomic DNA. Translation: ABF01633.1.
DQ473236 Genomic DNA. Translation: ABF01634.1.
DQ473238 Genomic DNA. Translation: ABF01636.1.
DQ473256 Genomic DNA. Translation: ABF01654.1.
DQ473258 Genomic DNA. Translation: ABF01656.1.
DQ473261 Genomic DNA. Translation: ABF01659.1.
DQ473262 Genomic DNA. Translation: ABF01660.1.
DQ473264 Genomic DNA. Translation: ABF01662.1.
DQ904040 Genomic DNA. Translation: ABK34557.1.
DQ904041 Genomic DNA. Translation: ABK34558.1.
DQ904042 Genomic DNA. Translation: ABK34559.1.
DQ904043 Genomic DNA. Translation: ABK34560.1.
DQ904044 Genomic DNA. Translation: ABK34561.1.
DQ904046 Genomic DNA. Translation: ABK34563.1.
DQ904048 Genomic DNA. Translation: ABK34565.1.
DQ904050 Genomic DNA. Translation: ABK34567.1.
DQ904053 Genomic DNA. Translation: ABK34570.1.
DQ904080 Genomic DNA. Translation: ABK34597.1.
DQ904082 Genomic DNA. Translation: ABK34599.1.
DQ904084 Genomic DNA. Translation: ABK34601.1.
DQ904086 Genomic DNA. Translation: ABK34603.1.
DQ904088 Genomic DNA. Translation: ABK34605.1.
DQ904169 Genomic DNA. Translation: ABK34686.1.
DQ904171 Genomic DNA. Translation: ABK34688.1.
DQ904173 Genomic DNA. Translation: ABK34690.1.
DQ904175 Genomic DNA. Translation: ABK34692.1.
DQ904177 Genomic DNA. Translation: ABK34694.1.
DQ904179 Genomic DNA. Translation: ABK34696.1.
DQ904181 Genomic DNA. Translation: ABK34698.1.
DQ904183 Genomic DNA. Translation: ABK34700.1.
DQ904185 Genomic DNA. Translation: ABK34702.1.
DQ904187 Genomic DNA. Translation: ABK34704.1.
DQ904220 Genomic DNA. Translation: ABK34737.1.
RefSeqiNP_000006.2. NM_000015.2.
UniGeneiHs.2.

Genome annotation databases

GeneIDi10.
KEGGihsa:10.
UCSCiuc003wyw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ472738 Genomic DNA. Translation: ABF01136.1.
DQ472742 Genomic DNA. Translation: ABF01140.1.
DQ472746 Genomic DNA. Translation: ABF01144.1.
DQ472749 Genomic DNA. Translation: ABF01147.1.
DQ472754 Genomic DNA. Translation: ABF01152.1.
DQ472755 Genomic DNA. Translation: ABF01153.1.
DQ472768 Genomic DNA. Translation: ABF01166.1.
DQ472778 Genomic DNA. Translation: ABF01176.1.
DQ472793 Genomic DNA. Translation: ABF01191.1.
DQ472796 Genomic DNA. Translation: ABF01194.1.
DQ472798 Genomic DNA. Translation: ABF01196.1.
DQ472804 Genomic DNA. Translation: ABF01202.1.
DQ472808 Genomic DNA. Translation: ABF01206.1.
DQ472812 Genomic DNA. Translation: ABF01210.1.
DQ472813 Genomic DNA. Translation: ABF01211.1.
DQ472816 Genomic DNA. Translation: ABF01214.1.
DQ472820 Genomic DNA. Translation: ABF01218.1.
DQ472832 Genomic DNA. Translation: ABF01230.1.
DQ472864 Genomic DNA. Translation: ABF01262.1.
DQ472868 Genomic DNA. Translation: ABF01266.1.
DQ472869 Genomic DNA. Translation: ABF01267.1.
DQ472873 Genomic DNA. Translation: ABF01271.1.
DQ472881 Genomic DNA. Translation: ABF01279.1.
DQ472892 Genomic DNA. Translation: ABF01290.1.
DQ472906 Genomic DNA. Translation: ABF01304.1.
DQ472914 Genomic DNA. Translation: ABF01312.1.
DQ472929 Genomic DNA. Translation: ABF01327.1.
DQ472941 Genomic DNA. Translation: ABF01339.1.
DQ472949 Genomic DNA. Translation: ABF01347.1.
DQ472951 Genomic DNA. Translation: ABF01349.1.
DQ472952 Genomic DNA. Translation: ABF01350.1.
DQ472961 Genomic DNA. Translation: ABF01359.1.
DQ472964 Genomic DNA. Translation: ABF01362.1.
DQ472980 Genomic DNA. Translation: ABF01378.1.
DQ472996 Genomic DNA. Translation: ABF01394.1.
DQ473006 Genomic DNA. Translation: ABF01404.1.
DQ473012 Genomic DNA. Translation: ABF01410.1.
DQ473015 Genomic DNA. Translation: ABF01413.1.
DQ473016 Genomic DNA. Translation: ABF01414.1.
DQ473026 Genomic DNA. Translation: ABF01424.1.
DQ473027 Genomic DNA. Translation: ABF01425.1.
DQ473030 Genomic DNA. Translation: ABF01428.1.
DQ473031 Genomic DNA. Translation: ABF01429.1.
DQ473034 Genomic DNA. Translation: ABF01432.1.
DQ473039 Genomic DNA. Translation: ABF01437.1.
DQ473044 Genomic DNA. Translation: ABF01442.1.
DQ473095 Genomic DNA. Translation: ABF01493.1.
DQ473107 Genomic DNA. Translation: ABF01505.1.
DQ473111 Genomic DNA. Translation: ABF01509.1.
DQ473112 Genomic DNA. Translation: ABF01510.1.
DQ473113 Genomic DNA. Translation: ABF01511.1.
DQ473114 Genomic DNA. Translation: ABF01512.1.
DQ473115 Genomic DNA. Translation: ABF01513.1.
DQ473130 Genomic DNA. Translation: ABF01528.1.
DQ473134 Genomic DNA. Translation: ABF01532.1.
DQ473136 Genomic DNA. Translation: ABF01534.1.
DQ473139 Genomic DNA. Translation: ABF01537.1.
DQ473143 Genomic DNA. Translation: ABF01541.1.
DQ473144 Genomic DNA. Translation: ABF01542.1.
DQ473146 Genomic DNA. Translation: ABF01544.1.
DQ473149 Genomic DNA. Translation: ABF01547.1.
DQ473152 Genomic DNA. Translation: ABF01550.1.
DQ473153 Genomic DNA. Translation: ABF01551.1.
DQ473154 Genomic DNA. Translation: ABF01552.1.
DQ473155 Genomic DNA. Translation: ABF01553.1.
DQ473159 Genomic DNA. Translation: ABF01557.1.
DQ473163 Genomic DNA. Translation: ABF01561.1.
DQ473187 Genomic DNA. Translation: ABF01585.1.
DQ473208 Genomic DNA. Translation: ABF01606.1.
DQ473212 Genomic DNA. Translation: ABF01610.1.
DQ473213 Genomic DNA. Translation: ABF01611.1.
DQ473216 Genomic DNA. Translation: ABF01614.1.
DQ473217 Genomic DNA. Translation: ABF01615.1.
DQ473219 Genomic DNA. Translation: ABF01617.1.
DQ473230 Genomic DNA. Translation: ABF01628.1.
DQ473233 Genomic DNA. Translation: ABF01631.1.
DQ473235 Genomic DNA. Translation: ABF01633.1.
DQ473236 Genomic DNA. Translation: ABF01634.1.
DQ473238 Genomic DNA. Translation: ABF01636.1.
DQ473256 Genomic DNA. Translation: ABF01654.1.
DQ473258 Genomic DNA. Translation: ABF01656.1.
DQ473261 Genomic DNA. Translation: ABF01659.1.
DQ473262 Genomic DNA. Translation: ABF01660.1.
DQ473264 Genomic DNA. Translation: ABF01662.1.
DQ904040 Genomic DNA. Translation: ABK34557.1.
DQ904041 Genomic DNA. Translation: ABK34558.1.
DQ904042 Genomic DNA. Translation: ABK34559.1.
DQ904043 Genomic DNA. Translation: ABK34560.1.
DQ904044 Genomic DNA. Translation: ABK34561.1.
DQ904046 Genomic DNA. Translation: ABK34563.1.
DQ904048 Genomic DNA. Translation: ABK34565.1.
DQ904050 Genomic DNA. Translation: ABK34567.1.
DQ904053 Genomic DNA. Translation: ABK34570.1.
DQ904080 Genomic DNA. Translation: ABK34597.1.
DQ904082 Genomic DNA. Translation: ABK34599.1.
DQ904084 Genomic DNA. Translation: ABK34601.1.
DQ904086 Genomic DNA. Translation: ABK34603.1.
DQ904088 Genomic DNA. Translation: ABK34605.1.
DQ904169 Genomic DNA. Translation: ABK34686.1.
DQ904171 Genomic DNA. Translation: ABK34688.1.
DQ904173 Genomic DNA. Translation: ABK34690.1.
DQ904175 Genomic DNA. Translation: ABK34692.1.
DQ904177 Genomic DNA. Translation: ABK34694.1.
DQ904179 Genomic DNA. Translation: ABK34696.1.
DQ904181 Genomic DNA. Translation: ABK34698.1.
DQ904183 Genomic DNA. Translation: ABK34700.1.
DQ904185 Genomic DNA. Translation: ABK34702.1.
DQ904187 Genomic DNA. Translation: ABK34704.1.
DQ904220 Genomic DNA. Translation: ABK34737.1.
RefSeqiNP_000006.2. NM_000015.2.
UniGeneiHs.2.

3D structure databases

ProteinModelPortaliA4Z6T7.
SMRiA4Z6T7. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000286479.

Protocols and materials databases

DNASUi10.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10.
KEGGihsa:10.
UCSCiuc003wyw.1. human.

Organism-specific databases

CTDi10.
PharmGKBiPA18.

Phylogenomic databases

GeneTreeiENSGT00390000012054.
HOVERGENiHBG000165.
KOiK00622.
OMAiDHIVRRN.
PhylomeDBiA4Z6T7.

Miscellaneous databases

GenomeRNAii10.
NextBioi17.

Gene expression databases

BgeeiA4Z6T7.
ExpressionAtlasiA4Z6T7. baseline and differential.
GenevisibleiA4Z6T7. HS.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.
ProtoNetiSearch...

Publicationsi

  1. "Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene."
    Patin E., Harmant C., Quintana-Murci L.
    Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AKELE2404-1Imported, AKELE2405-2Imported, AKELE2406-1Imported, AKELE2412-1Imported, AKELE2412-2Imported, AKELE2414-1Imported, AKELE2414-2Imported, AKELE2416-1Imported, AKELE2418-2Imported, BAKOLA280401-1Imported, BAKOLA400201-1Imported, BAKOLA400401-1Imported, BAKOLA801002-2Imported, BAKOLA880701-2Imported, BAKOLA940203-1Imported, BAKOLA950105-1Imported, BAKOLA950106-2Imported, BEDZAN01-1Imported, BEDZAN21-1Imported, BEDZAN24-1Imported, BEDZAN24-2Imported, BEDZAN29-2Imported, BEDZAN35-2Imported, BEDZAN50-1Imported, BIAKA0757-1Imported, BIAKA0764-1Imported, BIAKA0806-2Imported, BIAKA1700-2Imported, C.BAKA01-1Imported, C.BAKA03-1Imported, C.BAKA06-1Imported, C.BAKA07-2Imported, C.BAKA104-1Imported, C.BAKA104-2Imported, C.BAKA26-1Imported, C.BAKA59-1Imported, C.BAKA95-2Imported, C.BAKA98-1Imported, C.BAKA99-1Imported, CHAGGA4127-2Imported, CHAGGA4128-2Imported, CHAGGA4129-1Imported, CHAGGA4133-2Imported, CHAGGA4135-1Imported, CHAGGA4143-1Imported, CHAGGA4151-1Imported, CHAGGA4156-1Imported, G.BAKA0907-1Imported, G.BAKA0914-1Imported, G.BAKA0917-1Imported, G.BAKA0917-2Imported, G.BAKA0924-1Imported, G.BAKA0929-1Imported, MBUTI1037-1Imported, NGUMBA24-2Imported, NGUMBA45-2Imported, NGUMBA59-2Imported, NGUMBA60-1Imported, NGUMBA60-2Imported, NGUMBA64-1Imported, NGUMBA64-2Imported, SAN0987-1Imported, SAN0987-2Imported, SAN0988-1Imported, SAN0988-2Imported, SAN0992-2Imported, SAN1032-2Imported, SOMALI18-2Imported, YORUBA3846-1Imported, YORUBA3848-1Imported, YORUBA3848-2Imported, YORUBA3850-1Imported, YORUBA3850-2Imported, YORUBA3851-2Imported, YORUBA3858-1Imported, YORUBA3859-2Imported, YORUBA3860-2Imported, YORUBA3878-1Imported, YORUBA3879-1Imported, YORUBA3888-1Imported, YORUBA3889-1Imported, YORUBA3891-2Imported, YORUBA3892-1Imported and YORUBA3893-1Imported.
  2. "Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history."
    Sabbagh A., Langaney A., Darlu P., Gerard N., Krishnamoorthy R., Poloni E.S.
    BMC Genet. 9:21-21(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MAN1_12A_1Imported, MAN1_12A_2Imported, MAN21_12AImported, MAN22_12AImported, MAN23_12AImported, MAN24_12AImported, MAN25_12AImported, MAN2_12A_1Imported, MAN2_12A_2Imported, MAN3_12AImported, MAN4_12AImported, MAN5_12AImported, MAN65_12AImported, MAN66_12AImported, MAN67_12AImported, MAN68_12AImported, MAN69_12AImported, MAN6_12AImported, MAN70_12AImported, MAN71_12AImported, MAN72_12AImported, MAN73_12AImported, MAN74_12AImported, MAN7_12AImported and MAN91_12AImported.

Entry informationi

Entry nameiA4Z6T7_HUMAN
AccessioniPrimary (citable) accession number: A4Z6T7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 24, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.