A4Z6T7 (A4Z6T7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Arylamine N-acetyltransferase 2 EMBL ABF01136.1

Gene names

Name:

NAT2 EMBL ABF01136.1

Organism

Homo sapiens (Human) EMBL ABF01136.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the arylamine N-acetyltransferase family. RuleBase RU003452

Ontologies

Keywords
Molecular function	Acyltransferase RuleBase RU003452 Transferase
Gene Ontology (GO)
Molecular_function	acetyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4Z6T7 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: FAEE3BC2107F000E	FASTA	290	33,571
	10 20 30 40 50 60 MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL GLEAIFDHIV 70 80 90 100 110 120 RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK YSTGMVHLLL QVTIDGRNYI 130 140 150 160 170 180 VDAGSGSSSQ MWQPLELISG KDQPQVPCIF CLTEERGIWY LDQIRREQYI TNKEFLNSHL 190 200 210 220 230 240 LPKKKHQKIY LFTLEPRTIE DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT 250 260 270 280 290 YRKFNYKDNT DLVEFKTLTE EEVEEVLRNI FKISLGRNLV PKPGDGSLTI

References

[1]	"Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene." Patin E., Harmant C., Quintana-Murci L. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: AKELE2404-1 EMBL ABF01410.1, AKELE2405-2 EMBL ABF01413.1, AKELE2406-1 EMBL ABF01414.1, AKELE2412-1 EMBL ABF01424.1, AKELE2412-2 EMBL ABF01425.1, AKELE2414-1 EMBL ABF01428.1, AKELE2414-2 EMBL ABF01429.1, AKELE2416-1 EMBL ABF01432.1, AKELE2418-2 EMBL ABF01437.1, BAKOLA280401-1 EMBL ABF01528.1, BAKOLA400201-1 EMBL ABF01532.1, BAKOLA400401-1 EMBL ABF01534.1, BAKOLA801002-2 EMBL ABF01537.1, BAKOLA880701-2 EMBL ABF01541.1, BAKOLA940203-1 EMBL ABF01542.1, BAKOLA950105-1 EMBL ABF01544.1, BAKOLA950106-2 EMBL ABF01547.1, BEDZAN01-1 EMBL ABF01230.1, BEDZAN21-1 EMBL ABF01262.1, BEDZAN24-1 EMBL ABF01266.1, BEDZAN24-2 EMBL ABF01267.1, BEDZAN29-2 EMBL ABF01271.1, BEDZAN35-2 EMBL ABF01279.1, BEDZAN50-1 EMBL ABF01290.1, BIAKA0757-1 EMBL ABF01304.1, BIAKA0764-1 EMBL ABF01312.1, BIAKA0806-2 EMBL ABF01327.1, BIAKA1700-2 EMBL ABF01339.1, C.BAKA01-1 EMBL ABF01136.1, C.BAKA03-1 EMBL ABF01140.1, C.BAKA06-1 EMBL ABF01144.1, C.BAKA07-2 EMBL ABF01147.1, C.BAKA104-1 EMBL ABF01152.1, C.BAKA104-2 EMBL ABF01153.1, C.BAKA26-1 EMBL ABF01166.1, C.BAKA59-1 EMBL ABF01176.1, C.BAKA95-2 EMBL ABF01191.1, C.BAKA98-1 EMBL ABF01194.1, C.BAKA99-1 EMBL ABF01196.1, CHAGGA4127-2 EMBL ABF01347.1, CHAGGA4128-2 EMBL ABF01349.1, CHAGGA4129-1 EMBL ABF01350.1, CHAGGA4133-2 EMBL ABF01359.1, CHAGGA4135-1 EMBL ABF01362.1, CHAGGA4143-1 EMBL ABF01378.1, CHAGGA4151-1 EMBL ABF01394.1, CHAGGA4156-1 EMBL ABF01404.1, G.BAKA0907-1 EMBL ABF01202.1, G.BAKA0914-1 EMBL ABF01206.1, G.BAKA0917-1 EMBL ABF01210.1, G.BAKA0917-2 EMBL ABF01211.1, G.BAKA0924-1 EMBL ABF01214.1, G.BAKA0929-1 EMBL ABF01218.1, MBUTI1037-1 EMBL ABF01442.1, NGUMBA24-2 EMBL ABF01493.1, NGUMBA45-2 EMBL ABF01505.1, NGUMBA59-2 EMBL ABF01509.1, NGUMBA60-1 EMBL ABF01510.1, NGUMBA60-2 EMBL ABF01511.1, NGUMBA64-1 EMBL ABF01512.1, NGUMBA64-2 EMBL ABF01513.1, SAN0987-1 EMBL ABF01550.1, SAN0987-2 EMBL ABF01551.1, SAN0988-1 EMBL ABF01552.1, SAN0988-2 EMBL ABF01553.1, SAN0992-2 EMBL ABF01557.1, SAN1032-2 EMBL ABF01561.1, SOMALI18-2 EMBL ABF01585.1, YORUBA3846-1 EMBL ABF01606.1, YORUBA3848-1 EMBL ABF01610.1, YORUBA3848-2 EMBL ABF01611.1, YORUBA3850-1 EMBL ABF01614.1, YORUBA3850-2 EMBL ABF01615.1, YORUBA3851-2 EMBL ABF01617.1, YORUBA3858-1 EMBL ABF01628.1, YORUBA3859-2 EMBL ABF01631.1, YORUBA3860-2 EMBL ABF01633.1, YORUBA3878-1 EMBL ABF01634.1, YORUBA3879-1 EMBL ABF01636.1, YORUBA3888-1 EMBL ABF01654.1, YORUBA3889-1 EMBL ABF01656.1, YORUBA3891-2 EMBL ABF01659.1, YORUBA3892-1 EMBL ABF01660.1 and YORUBA3893-1 EMBL ABF01662.1.
[2]	"Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history." Sabbagh A., Langaney A., Darlu P., Gerard N., Krishnamoorthy R., Poloni E.S. BMC Genet. 9:21-21(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: MAN1_12A_1 EMBL ABK34557.1, MAN1_12A_2 EMBL ABK34558.1, MAN21_12A EMBL ABK34597.1, MAN22_12A EMBL ABK34599.1, MAN23_12A EMBL ABK34601.1, MAN24_12A EMBL ABK34603.1, MAN25_12A EMBL ABK34605.1, MAN2_12A_1 EMBL ABK34559.1, MAN2_12A_2 EMBL ABK34560.1, MAN3_12A EMBL ABK34561.1, MAN4_12A EMBL ABK34563.1, MAN5_12A EMBL ABK34565.1, MAN65_12A EMBL ABK34686.1, MAN66_12A EMBL ABK34688.1, MAN67_12A EMBL ABK34690.1, MAN68_12A EMBL ABK34692.1, MAN69_12A EMBL ABK34694.1, MAN6_12A EMBL ABK34567.1, MAN70_12A EMBL ABK34696.1, MAN71_12A EMBL ABK34698.1, MAN72_12A EMBL ABK34700.1, MAN73_12A EMBL ABK34702.1, MAN74_12A EMBL ABK34704.1, MAN7_12A EMBL ABK34570.1 and MAN91_12A EMBL ABK34737.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ472738 Genomic DNA. Translation: ABF01136.1. DQ472742 Genomic DNA. Translation: ABF01140.1. DQ472746 Genomic DNA. Translation: ABF01144.1. DQ472749 Genomic DNA. Translation: ABF01147.1. DQ472754 Genomic DNA. Translation: ABF01152.1. DQ472755 Genomic DNA. Translation: ABF01153.1. DQ472768 Genomic DNA. Translation: ABF01166.1. DQ472778 Genomic DNA. Translation: ABF01176.1. DQ472793 Genomic DNA. Translation: ABF01191.1. DQ472796 Genomic DNA. Translation: ABF01194.1. DQ472798 Genomic DNA. Translation: ABF01196.1. DQ472804 Genomic DNA. Translation: ABF01202.1. DQ472808 Genomic DNA. Translation: ABF01206.1. DQ472812 Genomic DNA. Translation: ABF01210.1. DQ472813 Genomic DNA. Translation: ABF01211.1. DQ472816 Genomic DNA. Translation: ABF01214.1. DQ472820 Genomic DNA. Translation: ABF01218.1. DQ472832 Genomic DNA. Translation: ABF01230.1. DQ472864 Genomic DNA. Translation: ABF01262.1. DQ472868 Genomic DNA. Translation: ABF01266.1. DQ472869 Genomic DNA. Translation: ABF01267.1. DQ472873 Genomic DNA. Translation: ABF01271.1. DQ472881 Genomic DNA. Translation: ABF01279.1. DQ472892 Genomic DNA. Translation: ABF01290.1. DQ472906 Genomic DNA. Translation: ABF01304.1. DQ472914 Genomic DNA. Translation: ABF01312.1. DQ472929 Genomic DNA. Translation: ABF01327.1. DQ472941 Genomic DNA. Translation: ABF01339.1. DQ472949 Genomic DNA. Translation: ABF01347.1. DQ472951 Genomic DNA. Translation: ABF01349.1. DQ472952 Genomic DNA. Translation: ABF01350.1. DQ472961 Genomic DNA. Translation: ABF01359.1. DQ472964 Genomic DNA. Translation: ABF01362.1. DQ472980 Genomic DNA. Translation: ABF01378.1. DQ472996 Genomic DNA. Translation: ABF01394.1. DQ473006 Genomic DNA. Translation: ABF01404.1. DQ473012 Genomic DNA. Translation: ABF01410.1. DQ473015 Genomic DNA. Translation: ABF01413.1. DQ473016 Genomic DNA. Translation: ABF01414.1. DQ473026 Genomic DNA. Translation: ABF01424.1. DQ473027 Genomic DNA. Translation: ABF01425.1. DQ473030 Genomic DNA. Translation: ABF01428.1. DQ473031 Genomic DNA. Translation: ABF01429.1. DQ473034 Genomic DNA. Translation: ABF01432.1. DQ473039 Genomic DNA. Translation: ABF01437.1. DQ473044 Genomic DNA. Translation: ABF01442.1. DQ473095 Genomic DNA. Translation: ABF01493.1. DQ473107 Genomic DNA. Translation: ABF01505.1. DQ473111 Genomic DNA. Translation: ABF01509.1. DQ473112 Genomic DNA. Translation: ABF01510.1. DQ473113 Genomic DNA. Translation: ABF01511.1. DQ473114 Genomic DNA. Translation: ABF01512.1. DQ473115 Genomic DNA. Translation: ABF01513.1. DQ473130 Genomic DNA. Translation: ABF01528.1. DQ473134 Genomic DNA. Translation: ABF01532.1. DQ473136 Genomic DNA. Translation: ABF01534.1. DQ473139 Genomic DNA. Translation: ABF01537.1. DQ473143 Genomic DNA. Translation: ABF01541.1. DQ473144 Genomic DNA. Translation: ABF01542.1. DQ473146 Genomic DNA. Translation: ABF01544.1. DQ473149 Genomic DNA. Translation: ABF01547.1. DQ473152 Genomic DNA. Translation: ABF01550.1. DQ473153 Genomic DNA. Translation: ABF01551.1. DQ473154 Genomic DNA. Translation: ABF01552.1. DQ473155 Genomic DNA. Translation: ABF01553.1. DQ473159 Genomic DNA. Translation: ABF01557.1. DQ473163 Genomic DNA. Translation: ABF01561.1. DQ473187 Genomic DNA. Translation: ABF01585.1. DQ473208 Genomic DNA. Translation: ABF01606.1. DQ473212 Genomic DNA. Translation: ABF01610.1. DQ473213 Genomic DNA. Translation: ABF01611.1. DQ473216 Genomic DNA. Translation: ABF01614.1. DQ473217 Genomic DNA. Translation: ABF01615.1. DQ473219 Genomic DNA. Translation: ABF01617.1. DQ473230 Genomic DNA. Translation: ABF01628.1. DQ473233 Genomic DNA. Translation: ABF01631.1. DQ473235 Genomic DNA. Translation: ABF01633.1. DQ473236 Genomic DNA. Translation: ABF01634.1. DQ473238 Genomic DNA. Translation: ABF01636.1. DQ473256 Genomic DNA. Translation: ABF01654.1. DQ473258 Genomic DNA. Translation: ABF01656.1. DQ473261 Genomic DNA. Translation: ABF01659.1. DQ473262 Genomic DNA. Translation: ABF01660.1. DQ473264 Genomic DNA. Translation: ABF01662.1. DQ904040 Genomic DNA. Translation: ABK34557.1. DQ904041 Genomic DNA. Translation: ABK34558.1. DQ904042 Genomic DNA. Translation: ABK34559.1. DQ904043 Genomic DNA. Translation: ABK34560.1. DQ904044 Genomic DNA. Translation: ABK34561.1. DQ904046 Genomic DNA. Translation: ABK34563.1. DQ904048 Genomic DNA. Translation: ABK34565.1. DQ904050 Genomic DNA. Translation: ABK34567.1. DQ904053 Genomic DNA. Translation: ABK34570.1. DQ904080 Genomic DNA. Translation: ABK34597.1. DQ904082 Genomic DNA. Translation: ABK34599.1. DQ904084 Genomic DNA. Translation: ABK34601.1. DQ904086 Genomic DNA. Translation: ABK34603.1. DQ904088 Genomic DNA. Translation: ABK34605.1. DQ904169 Genomic DNA. Translation: ABK34686.1. DQ904171 Genomic DNA. Translation: ABK34688.1. DQ904173 Genomic DNA. Translation: ABK34690.1. DQ904175 Genomic DNA. Translation: ABK34692.1. DQ904177 Genomic DNA. Translation: ABK34694.1. DQ904179 Genomic DNA. Translation: ABK34696.1. DQ904181 Genomic DNA. Translation: ABK34698.1. DQ904183 Genomic DNA. Translation: ABK34700.1. DQ904185 Genomic DNA. Translation: ABK34702.1. DQ904187 Genomic DNA. Translation: ABK34704.1. DQ904220 Genomic DNA. Translation: ABK34737.1.
IPI	IPI00004421.
RefSeq	NP_000006.2. NM_000015.2.
UniGene	Hs.2.
3D structure databases
ProteinModelPortal	A4Z6T7.
SMR	A4Z6T7. Positions 2-290.
ModBase	Search...
Protein-protein interaction databases
STRING	A4Z6T7.
Protocols and materials databases
DNASU	10.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10.
KEGG	hsa:10.
UCSC	uc003wyw.1. human.
Organism-specific databases
CTD	10.
PharmGKB	PA18.
Phylogenomic databases
HOVERGEN	HBG000165.
KO	K00622.
OMA	DHIVRRN.
Gene expression databases
ArrayExpress	A4Z6T7.
Bgee	A4Z6T7.
Family and domain databases
InterPro	IPR001447. Arylamine_N-AcTrfase. [Graphical view]
PANTHER	PTHR11786. PTHR11786. 1 hit.
Pfam	PF00797. Acetyltransf_2. 1 hit. [Graphical view]
PRINTS	PR01543. ANATRNSFRASE.
ProtoNet	Search...
Other
GenomeRNAi	10.
NextBio	17.

Entry information

Entry name

A4Z6T7_HUMAN

Accession

Primary (citable) accession number: A4Z6T7

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	March 6, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.