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A4Z3J7 (A4Z3J7_BRASO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA EMBL CAL80723.1
Synonyms:msrA2 HAMAP MF_01401
Ordered Locus Names:BRADO7141
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site541 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A4Z3J7 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 6099155D0CCDCE84

FASTA21823,431
        10         20         30         40         50         60 
MFFMRKPAAL PSAAEALPGR AQPIPTATKH FVNGRALLPP YPAGLEQAVF GLGCFWGAER 

        70         80         90        100        110        120 
KFWQLGNGIH VTAVGYAGGH TPNPTYEEVC SGLTAHTEVV LVVFDPKIIS YERLLKTFWE 

       130        140        150        160        170        180 
SHDPTQGMRQ GNDVGTQYRS AVYTFSEAQR ETAEASKQAY EKALRAKGLG AITTEIAPAG 

       190        200        210 
PFYFAEDYHQ QYLAKNPAGY CGLGGTGVAC PIGVGVSA 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU234118 Genomic DNA. Translation: CAL80723.1.
RefSeqYP_001208938.1. NC_009445.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4Z3J7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5117453.
GenomeReviewsGene locus BRADO7141 in contig CU234118_GR.
KEGGbra:BRADO7141.
PATRIC21230103. VBIBraSp122330_6835.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMASAIYCTS.
ProtClustDBPRK00058.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4Z3J7_BRASO
AccessionPrimary (citable) accession number: A4Z3J7
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)