A4Z2A0 (A4Z2A0_BRASO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase (ALAS) EMBL CAL80276.1
EC=2.3.1.37 EMBL CAL80276.1

Gene names

Name:	hemA EMBL CAL80276.1
Ordered Locus Names:	BRADO6672

Organism

Bradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]

Taxonomic identifier

114615 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Acyltransferase EMBL CAL80276.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4Z2A0 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 8A5C5380534F4BC9	FASTA	409	44,560
	10 20 30 40 50 60 MDYSQYFSAA LGRLHDERRY RVFADLERIA GRFPHATWHS PNGPRNVVIW CSNDYLGMGQ 70 80 90 100 110 120 HPKVVGAMVE TATRVGTGAG GTRNIAGTHH PLVQLEAELA DLHGKEAALL FTSGYVSNQT 130 140 150 160 170 180 GIATLAKLIP DCLILSDALN HNSMIEGVRQ SGCERQIWRH NDLAHLEQLL IAAGPSRPKL 190 200 210 220 230 240 IACESLYSMD GDVAPLAAIC DLAERYNAMT YVDEVHAVGM YGARGGGIAE RDGVMHRIDI 250 260 270 280 290 300 LEGTLAKAFG CLGGYIAAKG EIIDAVRSYA PGFIFTTALP PPICSAATAA IKHLKSSSWE 310 320 330 340 350 360 RERHQDRAAR VKAILNAAGL PVMDNDTHIV PLFVGDPEKC KQASDLLLEE HGIYIQPINY 370 380 390 400 PTVAKGTERL RITPSPYHDD GLIDRLAEAL LQVWERLGLA LHKKPLAAE

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU234118 Genomic DNA. Translation: CAL80276.1.
RefSeq	YP_001208491.1. NC_009445.1.
3D structure databases
ProteinModelPortal	A4Z2A0.
ModBase	Search...
Protein-protein interaction databases
STRING	A4Z2A0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5121308.
GenomeReviews	Gene locus BRADO6672 in contig CU234118_GR.
KEGG	bra:BRADO6672.
PATRIC	21229201. VBIBraSp122330_6386.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0156.
HOGENOM	HBG649839.
OMA	HATWHSP.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4Z2A0_BRASO

Accession

Primary (citable) accession number: A4Z2A0

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)