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A4YZK0

- A4YZK0_BRASO

UniProt

A4YZK0 - A4YZK0_BRASO

Protein
Submitted name:

D-alanine-D-alanine ligase, affects cell division

Gene

ddlB

Organism
Bradyrhizobium sp. (strain ORS278)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell division Source: UniProtKB-KW
    2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    3. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionImported, Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBSP114615:GJN5-5401-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine-D-alanine ligase, affects cell divisionImported (EC:6.3.2.4Imported)
    Gene namesi
    Name:ddlBImported
    Ordered Locus Names:BRADO5656Imported
    OrganismiBradyrhizobium sp. (strain ORS278)Imported
    Taxonomic identifieri114615 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000001994: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi114615.BRADO5656.

    Structurei

    3D structure databases

    ProteinModelPortaliA4YZK0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    HOGENOMiHOG000011592.
    KOiK01921.
    OMAiDYTARYT.
    OrthoDBiEOG6ND0KB.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4YZK0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRTTILFGGS NKERLVSVAS AKALHAALPE ADLWFWEADD TVQQASGPAL    50
    VAHAKPFEEP FTADGVRIGT LAEALDRARA EDRILVLGLH GGRAENGELQ 100
    VMCEMRGVPF TGSSSAASHL AFDKVAAKRF AVLGGVTAAE GVALDNAETA 150
    LARYGKLIAK PVKDGSSFGL IFVNAKQDLV AVKAAAATEE YLIEPFVTGK 200
    EATCGVLEQA DGSLIALPPI EILPADGAFN YFAKYLAAAT KEICPGRFNP 250
    EVTAALQREA IKAHRALSCG GYSRTDFIVS ADGPVYLETN TLPGLTAASL 300
    YPKALAAQGI PFADFLQQQI ALAERRVRH 329
    Length:329
    Mass (Da):34,796
    Last modified:May 29, 2007 - v1
    Checksum:iD5388FBD6E0ABEE0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU234118 Genomic DNA. Translation: CAL79326.1.
    RefSeqiWP_012029233.1. NC_009445.1.
    YP_001207543.1. NC_009445.1.

    Genome annotation databases

    EnsemblBacteriaiCAL79326; CAL79326; BRADO5656.
    GeneIDi5120086.
    KEGGibra:BRADO5656.
    PATRICi21227271. VBIBraSp122330_5432.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU234118 Genomic DNA. Translation: CAL79326.1 .
    RefSeqi WP_012029233.1. NC_009445.1.
    YP_001207543.1. NC_009445.1.

    3D structure databases

    ProteinModelPortali A4YZK0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 114615.BRADO5656.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL79326 ; CAL79326 ; BRADO5656 .
    GeneIDi 5120086.
    KEGGi bra:BRADO5656.
    PATRICi 21227271. VBIBraSp122330_5432.

    Phylogenomic databases

    eggNOGi COG1181.
    HOGENOMi HOG000011592.
    KOi K01921.
    OMAi DYTARYT.
    OrthoDBi EOG6ND0KB.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci BSP114615:GJN5-5401-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ORS278Imported.

    Entry informationi

    Entry nameiA4YZK0_BRASO
    AccessioniPrimary (citable) accession number: A4YZK0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 29, 2007
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3