A4YXZ8 (FENR_BRASO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2

Gene names

Ordered Locus Names:

BRADO5079

Organism

Bradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]

Taxonomic identifier

114615 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Ferredoxin--NADP reductase HAMAP MF_01685		PRO_0000364811
Sites
	Binding site	17	1	FAD By similarity
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	49	1	FAD By similarity
	Binding site	89	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	124	1	FAD; via amide nitrogen By similarity
	Binding site	289	1	FAD By similarity
	Binding site	330	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4YXZ8 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 907AB89552A52AF9	FASTA	342	36,983
	10 20 30 40 50 60 MSEAIKTDVL IIGAGPCGLF AVFELGLLDI KAHLIDILDK VGGQCAELYP EKPIYDIPGV 70 80 90 100 110 120 PMVTGQGLTD QLMEQIKPFS PTFHLGEMVS NVEKIGDPGF RVTTDAGKVF ECKVVVIAAG 130 140 150 160 170 180 GGSFQPKRPP VPGIEAYEGT SVFYAVRKME QFRGKNVVIV GGGDSALDWT LNLHPIAKRI 190 200 210 220 230 240 ALIHRRDDFR AAPHSVEQMR ALVASGKMDL RIGQVTALEG TNGQLSAATI KGNDNAVETI 250 260 270 280 290 300 PCEMMLPFFG LTMKLGPVAD WGIALEHNLI PVETSAFETS VPGIFAIGDI NTYPGKIKLI 310 320 330 340 LCGFHEGALM AQKAHRYVYP EKRLVFQYTT SSSSLQKKLG VN

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS278.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU234118 Genomic DNA. Translation: CAL78774.1.
RefSeq	YP_001206991.1. NC_009445.1.
3D structure databases
ProteinModelPortal	A4YXZ8.
ModBase	Search...
Protein-protein interaction databases
STRING	A4YXZ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5116016.
GenomeReviews	Gene locus BRADO5079 in contig CU234118_GR.
KEGG	bra:BRADO5079.
PATRIC	21226163. VBIBraSp122330_4879.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	SESAMAC.
ProtClustDB	CLSK863087.
Enzyme and pathway databases
BioCyc	BSP376:BRADO5079-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR_BRASO

Accession

Primary (citable) accession number: A4YXZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program