Reviewed, UniProtKB/Swiss-Prot A4YXZ8 (FENR_BRASO)

Names and origin

Protein names

Recommended name:
    Ferredoxin--NADP reductase
      Short name=Fd-NADP+ reductase
      Short name=FNR
    EC=1.18.1.2

Gene names

Ordered Locus Names:

BRADO5079

Organism

Bradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]

Taxonomic identifier

114615 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: HAMAP NADP or NADPH binding Inferred from electronic annotation. Source: HAMAP ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Ferredoxin--NADP reductase HAMAP MF_01685		PRO_0000364811
Sites
	Binding site	17	1	FAD By similarity
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	49	1	FAD By similarity
	Binding site	89	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	124	1	FAD; via amide nitrogen By similarity
	Binding site	289	1	FAD By similarity
	Binding site	330	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4YXZ8-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 907AB89552A52AF9	FASTA	342	36,983
	10 20 30 40 50 60 MSEAIKTDVL IIGAGPCGLF AVFELGLLDI KAHLIDILDK VGGQCAELYP EKPIYDIPGV 70 80 90 100 110 120 PMVTGQGLTD QLMEQIKPFS PTFHLGEMVS NVEKIGDPGF RVTTDAGKVF ECKVVVIAAG 130 140 150 160 170 180 GGSFQPKRPP VPGIEAYEGT SVFYAVRKME QFRGKNVVIV GGGDSALDWT LNLHPIAKRI 190 200 210 220 230 240 ALIHRRDDFR AAPHSVEQMR ALVASGKMDL RIGQVTALEG TNGQLSAATI KGNDNAVETI 250 260 270 280 290 300 PCEMMLPFFG LTMKLGPVAD WGIALEHNLI PVETSAFETS VPGIFAIGDI NTYPGKIKLI 310 320 330 340 LCGFHEGALM AQKAHRYVYP EKRLVFQYTT SSSSLQKKLG VN

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CU234118 Genomic DNA. Translation: CAL78774.1.
RefSeq	YP_001206991.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4YXZ8.
Genome annotation databases
GeneID	5116016.
GenomeReviews	Gene locus BRADO5079 in contig CU234118_GR.
KEGG	bra:BRADO5079.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DIAYYPG.
Family and domain databases
HAMAP	MF_01685. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR016040. NAD(P)-bd_dom. IPR001327. Pyr_OxRdtase_NAD_bd. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

FENR_BRASO

Accession

Primary (citable) accession number: A4YXZ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	May 29, 2007
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)