A4YXN2 (FCTA_BRASO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Formyl-coenzyme A transferase
Short name=Formyl-CoA transferase
EC=2.8.3.16

Gene names

Name:	frc
Ordered Locus Names:	BRADO4956

Organism

Bradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]

Taxonomic identifier

114615 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate By similarity. HAMAP MF_00742
Catalytic activity	Formyl-CoA + oxalate = formate + oxalyl-CoA. HAMAP MF_00742
Pathway	Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2. HAMAP MF_00742
Sequence similarities	Belongs to the CaiB/BaiF CoA-transferase family.

Ontologies

Keywords
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	formyl-CoA transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 425	425	Formyl-coenzyme A transferase HAMAP MF_00742		PRO_0000300986
Sites
	Active site	168	1	Nucleophile By similarity
	Binding site	96	1	Coenzyme A By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4YXN2 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 282D194B4929E61A	FASTA	425	46,620
	10 20 30 40 50 60 MTKALEGVRI LDFTHVQSGP TCTQLLAWFG ADVIKVERPG VGDITRGQLQ DIPNVDSLYF 70 80 90 100 110 120 TMLNHNKRSI TLDTKNPKGK EVLTELIKKC DVLVENFGPG VLDRMGFPWE KIQAINPKMI 130 140 150 160 170 180 VASIKGFGPG PYEDCKVYEN VAQCTGGAAS TTGFRDGLPL VTGAQIGDSG TGLHLALGIV 190 200 210 220 230 240 TALYQRTHTG RGQRVTAAMQ DGVLNLCRVK LRDQQRLDHG PLKEYSQFGE GVPFGDAVPR 250 260 270 280 290 300 AGNDSGGGQP GRILKCKGWE TDPNAYIYFI TQAPVWEKIC DVIGEPTWKT DPNYAKPAAR 310 320 330 340 350 360 LPRLNEIFGR IEQWTMTKTK FEAMDILNEF DIPCGPILSM KEIAEDESLR KTGTLVEVDH 370 380 390 400 410 420 PTRGKYLSVG NPIKLSDSPA DVTRSPLLGE HTDEILRQVL GFSDHQVAEI HDSGALDPPR KEAAE

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS278.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU234118 Genomic DNA. Translation: CAL78658.1.
RefSeq	YP_001206875.1. NC_009445.1.
3D structure databases
ProteinModelPortal	A4YXN2.
SMR	A4YXN2. Positions 1-416.
ModBase	Search...
Protein-protein interaction databases
STRING	A4YXN2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5116767.
GenomeReviews	Gene locus BRADO4956 in contig CU234118_GR.
KEGG	bra:BRADO4956.
PATRIC	21225923. VBIBraSp122330_4759.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1804.
HOGENOM	HBG659028.
OMA	QFGEGIP.
ProtClustDB	PRK05398.
Enzyme and pathway databases
BioCyc	BSP376:BRADO4956-MONOMER.
Family and domain databases
HAMAP	MF_00742. Formyl-CoA_transfer. [Tree]
InterPro	IPR003673. CoA-Trfase_fam_III. IPR023606. CoA-Trfase_III_dom. IPR017659. Formyl-CoA_transferase. [Graphical view]
Gene3D	G3DSA:3.40.50.10540. CoA-Trfase_fam_III. 1 hit.
KO	K07749.
PANTHER	PTHR11837. CAIB_BAIF. 1 hit.
Pfam	PF02515. CoA_transf_3. 1 hit. [Graphical view]
SUPFAM	SSF89796. CoA-Trfase_fam_III. 1 hit.
TIGRFAMs	TIGR03253. Oxalate_frc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FCTA_BRASO

Accession

Primary (citable) accession number: A4YXN2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program