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A4YV78

- SYR_BRASO

UniProt

A4YV78 - SYR_BRASO

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Bradyrhizobium sp. (strain ORS278)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSP114615:GJN5-3864-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BRADO4052
OrganismiBradyrhizobium sp. (strain ORS278)
Taxonomic identifieri114615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000001994: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 598598Arginine--tRNA ligasePRO_1000017994Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi114615.BRADO4052.

Structurei

3D structure databases

ProteinModelPortaliA4YV78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi139 – 14911"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiLCNVLAK.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4YV78-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVEQASTPYL FADMLARVHA ICAALAKSGG WPEGIDFSRV VVEPPRDPSH
60 70 80 90 100
GDMATNAAMV LAKEAKAKPR DLAEQIAERL RADELVAKVD VAGPGFINLT
110 120 130 140 150
LQPSVWSKAL ATILREGAAY GRVAPVPGAP KVNVEYVSAN PTGPMHVGHC
160 170 180 190 200
RGAVFGDALS SLLQFAGRDV TREYYINDAG AQVDVLARSA YLRYREALGE
210 220 230 240 250
DIGAIPEGLY PGDYLKPVGQ ALKTEHGDKL KAMPDAQWLP IVRDKAIAMM
260 270 280 290 300
MDEIKDDLAA LNIRHDVFFS ERSLITGGNN KVAETIDFLR ERGDVYEGRL
310 320 330 340 350
PPPKGAPVED WEDREQLLFR ATAFGDDVDR PLIKSDGSYT YFASDIANHR
360 370 380 390 400
HKFERGFADL IDVFGADHGG YIKRMQAAVK AVTAAQATLD VKVVQLVKLL
410 420 430 440 450
RNGEPVKMSK RSGDFVTLRE VVDEVGRDAV RFMMLYRKND AVLDFDLAKV
460 470 480 490 500
IEQSKDNPVF YVQYGHARGH SIFRNARESL PELPEEEGAR IAFLREAKLE
510 520 530 540 550
RLADSAEHDL LKRLALYPRT VESAAMAHEP HRIAFYLYEL ASEFHALWTR
560 570 580 590
GRDLPYLRFI IDDDAELTKA RLAMVQGVVS VLASGLAILG VNAPDAMR
Length:598
Mass (Da):66,094
Last modified:May 29, 2007 - v1
Checksum:iF2A577745ED05697
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL77804.1.
RefSeqiWP_011926937.1. NC_009445.1.
YP_001206029.1. NC_009445.1.

Genome annotation databases

EnsemblBacteriaiCAL77804; CAL77804; BRADO4052.
GeneIDi5121200.
KEGGibra:BRADO4052.
PATRICi21224187. VBIBraSp122330_3901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL77804.1 .
RefSeqi WP_011926937.1. NC_009445.1.
YP_001206029.1. NC_009445.1.

3D structure databases

ProteinModelPortali A4YV78.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 114615.BRADO4052.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL77804 ; CAL77804 ; BRADO4052 .
GeneIDi 5121200.
KEGGi bra:BRADO4052.
PATRICi 21224187. VBIBraSp122330_3901.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi LCNVLAK.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci BSP114615:GJN5-3864-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ORS278.

Entry informationi

Entry nameiSYR_BRASO
AccessioniPrimary (citable) accession number: A4YV78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3