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Protein

RNA-binding protein Hfq

Gene

hfq

Organism
Bradyrhizobium sp. (strain ORS 278)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Stress response

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein HfqUniRule annotation
Gene namesi
Name:hfqUniRule annotation
Ordered Locus Names:BRADO3855
OrganismiBradyrhizobium sp. (strain ORS 278)
Taxonomic identifieri114615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000001994 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000806561 – 82RNA-binding protein HfqAdd BLAST82

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi114615.BRADO3855.

Structurei

3D structure databases

ProteinModelPortaliA4YUP3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Hfq family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KW8. Bacteria.
COG1923. LUCA.
HOGENOMiHOG000004931.
KOiK03666.
OMAiRDGHAQL.
OrthoDBiPOG091H05GW.

Family and domain databases

CDDicd01716. Hfq. 1 hit.
HAMAPiMF_00436. Hfq. 1 hit.
InterProiIPR005001. Hfq.
IPR010920. LSM_dom.
[Graphical view]
PANTHERiPTHR34772:SF1. PTHR34772:SF1. 1 hit.
PfamiPF17209. Hfq. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
TIGRFAMsiTIGR02383. Hfq. 1 hit.

Sequencei

Sequence statusi: Complete.

A4YUP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAADRAQNLQ DTFLNHVRKT KTPLTIFLVN GVKLQGIVTW FDNFCLLLRR
60 70 80
DGHSQLVYKH AISTIMPGAP IQLFEGGEDA SA
Length:82
Mass (Da):9,141
Last modified:May 29, 2007 - v1
Checksum:i9561D97B2DCCF6B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL77619.1.
RefSeqiWP_006613906.1. NC_009445.1.

Genome annotation databases

EnsemblBacteriaiCAL77619; CAL77619; BRADO3855.
KEGGibra:BRADO3855.
PATRICi21223831. VBIBraSp122330_3726.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL77619.1.
RefSeqiWP_006613906.1. NC_009445.1.

3D structure databases

ProteinModelPortaliA4YUP3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi114615.BRADO3855.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL77619; CAL77619; BRADO3855.
KEGGibra:BRADO3855.
PATRICi21223831. VBIBraSp122330_3726.

Phylogenomic databases

eggNOGiENOG4105KW8. Bacteria.
COG1923. LUCA.
HOGENOMiHOG000004931.
KOiK03666.
OMAiRDGHAQL.
OrthoDBiPOG091H05GW.

Family and domain databases

CDDicd01716. Hfq. 1 hit.
HAMAPiMF_00436. Hfq. 1 hit.
InterProiIPR005001. Hfq.
IPR010920. LSM_dom.
[Graphical view]
PANTHERiPTHR34772:SF1. PTHR34772:SF1. 1 hit.
PfamiPF17209. Hfq. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
TIGRFAMsiTIGR02383. Hfq. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiHFQ_BRASO
AccessioniPrimary (citable) accession number: A4YUP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: November 2, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.