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A4YSB4 (A4YSB4_BRASO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 2 HAMAP MF_00223

EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 2 HAMAP MF_00223
Gene names
Name:folE EMBL CAL76790.1
Synonyms:folE2 HAMAP MF_00223
Ordered Locus Names:BRADO2984
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1231Zinc By similarity HAMAP MF_00223
Metal binding1261Zinc By similarity HAMAP MF_00223
Metal binding1941Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
A4YSB4 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 8546D2D6599ED802

FASTA23526,380
        10         20         30         40         50         60 
MDTLIKTLRA NKPEGKPSET KLAGERPAEL DPAEFLAAAV RADRPRPSRA EAEAAVYTLL 

        70         80         90        100        110        120 
NYIGEDPTRE GLIDTPRRVV EAYDELFQGY HQCPAEVLDR TFGETAGYDD FVLIRDIEFT 

       130        140        150        160        170        180 
SQCEHHMMPF YGRAHIAYTP VERVVGLSKL ARLTDIFARR LQTQEHLTAQ IAAAIDEVLK 

       190        200        210        220        230 
PRGVAVMIEA EHTCMSVRGV AKHGAVTFTS RFTGMFRDNP AEQSRFLSMV RSPQR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU234118 Genomic DNA. Translation: CAL76790.1.
RefSeqYP_001205027.1. NC_009445.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4YSB4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5117960.
GenomeReviewsGene locus BRADO2984 in contig CU234118_GR.
KEGGbra:BRADO2984.
PATRIC21222155. VBIBraSp122330_2899.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMAHEEMIIV.
ProtClustDBPRK09347.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4YSB4_BRASO
AccessionPrimary (citable) accession number: A4YSB4
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)