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A4YRL1

- TYPH_BRASO

UniProt

A4YRL1 - TYPH_BRASO

Protein

Putative thymidine phosphorylase

Gene

BRADO2724

Organism
Bradyrhizobium sp. (strain ORS278)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 2 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

    GO - Molecular functioni

    1. phosphorylase activity Source: InterPro
    2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pyrimidine nucleobase metabolic process Source: InterPro
    2. pyrimidine nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciBSP114615:GJN5-2582-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
    Alternative name(s):
    TdRPaseUniRule annotation
    Gene namesi
    Ordered Locus Names:BRADO2724
    OrganismiBradyrhizobium sp. (strain ORS278)
    Taxonomic identifieri114615 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000001994: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 509509Putative thymidine phosphorylasePRO_0000314698Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi114615.BRADO2724.

    Structurei

    3D structure databases

    ProteinModelPortaliA4YRL1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0213.
    HOGENOMiHOG000252767.
    KOiK00758.
    OrthoDBiEOG61ZTGG.

    Family and domain databases

    Gene3Di3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPiMF_00703. Thymid_phosp_2.
    InterProiIPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view]
    PANTHERiPTHR10515. PTHR10515. 1 hit.
    PfamiPF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000478. TP_PyNP. 1 hit.
    SMARTiSM00941. PYNP_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4YRL1-1 [UniParc]FASTAAdd to Basket

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    MSPADTARPQ LKIRSVALDT GRENVVVISR RSRALRPEVF SGFSRVELRC    50
    NSRTLLATLL ITDDDALVGP DEIGLSEPAL RRFAEPAGML ATVSPATPPE 100
    SLEAVRAKIR GETLSDEAIA AVIEDLAHYR YSDMEIAAFL IGSASFMTSG 150
    ELLALTHAMA NAGTQLTWPE PVVVDKHCIG GIPGNRTSMV VVPIVAAHGL 200
    TIPKTSSRAI TSPAGTADTM EVLARVNVGA EEMKSIVAAC NGCVIWGGHV 250
    NLSPADDILI SVERPLSLDT REQMVASILS KKLAAGSTHL LLDLPVGPTA 300
    KLTSGAEAMR LRKLFEFVGD RFGLKVEVIT TDGRQPIGHG IGPVLEARDV 350
    MAVLGNEPQA PADLREKSLR LAAHLLEYDP KLRGGAGYSR ARELLDSGAA 400
    LKQMQKIIDA QGPSAGRSEL GDLAFDVGAA SDGVVSAIDC LRLNRLARTA 450
    GAPVNKGAGI RLYKKIGDRV DQGEPLYRVF TCDPSEHDLA AAAASANNGY 500
    VLDGPNGPH 509
    Length:509
    Mass (Da):53,799
    Last modified:January 15, 2008 - v2
    Checksum:iAEA6FF85803CA15C
    GO

    Sequence cautioni

    The sequence CAL76537.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU234118 Genomic DNA. Translation: CAL76537.1. Different initiation.
    RefSeqiWP_011925743.1. NC_009445.1.
    YP_001204774.1. NC_009445.1.

    Genome annotation databases

    EnsemblBacteriaiCAL76537; CAL76537; BRADO2724.
    GeneIDi5118650.
    KEGGibra:BRADO2724.
    PATRICi21221631. VBIBraSp122330_2638.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU234118 Genomic DNA. Translation: CAL76537.1 . Different initiation.
    RefSeqi WP_011925743.1. NC_009445.1.
    YP_001204774.1. NC_009445.1.

    3D structure databases

    ProteinModelPortali A4YRL1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 114615.BRADO2724.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL76537 ; CAL76537 ; BRADO2724 .
    GeneIDi 5118650.
    KEGGi bra:BRADO2724.
    PATRICi 21221631. VBIBraSp122330_2638.

    Phylogenomic databases

    eggNOGi COG0213.
    HOGENOMi HOG000252767.
    KOi K00758.
    OrthoDBi EOG61ZTGG.

    Enzyme and pathway databases

    BioCyci BSP114615:GJN5-2582-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPi MF_00703. Thymid_phosp_2.
    InterProi IPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view ]
    PANTHERi PTHR10515. PTHR10515. 1 hit.
    Pfami PF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000478. TP_PyNP. 1 hit.
    SMARTi SM00941. PYNP_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ORS278.

    Entry informationi

    Entry nameiTYPH_BRASO
    AccessioniPrimary (citable) accession number: A4YRL1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3