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A4YRL1 (TYPH_BRASO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:BRADO2724
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length509 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence caution

The sequence CAL76537.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 509509Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000314698

Sequences

Sequence LengthMass (Da)Tools
A4YRL1 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: AEA6FF85803CA15C

FASTA50953,799
        10         20         30         40         50         60 
MSPADTARPQ LKIRSVALDT GRENVVVISR RSRALRPEVF SGFSRVELRC NSRTLLATLL 

        70         80         90        100        110        120 
ITDDDALVGP DEIGLSEPAL RRFAEPAGML ATVSPATPPE SLEAVRAKIR GETLSDEAIA 

       130        140        150        160        170        180 
AVIEDLAHYR YSDMEIAAFL IGSASFMTSG ELLALTHAMA NAGTQLTWPE PVVVDKHCIG 

       190        200        210        220        230        240 
GIPGNRTSMV VVPIVAAHGL TIPKTSSRAI TSPAGTADTM EVLARVNVGA EEMKSIVAAC 

       250        260        270        280        290        300 
NGCVIWGGHV NLSPADDILI SVERPLSLDT REQMVASILS KKLAAGSTHL LLDLPVGPTA 

       310        320        330        340        350        360 
KLTSGAEAMR LRKLFEFVGD RFGLKVEVIT TDGRQPIGHG IGPVLEARDV MAVLGNEPQA 

       370        380        390        400        410        420 
PADLREKSLR LAAHLLEYDP KLRGGAGYSR ARELLDSGAA LKQMQKIIDA QGPSAGRSEL 

       430        440        450        460        470        480 
GDLAFDVGAA SDGVVSAIDC LRLNRLARTA GAPVNKGAGI RLYKKIGDRV DQGEPLYRVF 

       490        500 
TCDPSEHDLA AAAASANNGY VLDGPNGPH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU234118 Genomic DNA. Translation: CAL76537.1. Different initiation.
RefSeqYP_001204774.1. NC_009445.1.

3D structure databases

ProteinModelPortalA4YRL1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING114615.BRADO2724.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL76537; CAL76537; BRADO2724.
GeneID5118650.
KEGGbra:BRADO2724.
PATRIC21221631. VBIBraSp122330_2638.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycBSP114615:GJN5-2582-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_BRASO
AccessionPrimary (citable) accession number: A4YRL1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families