Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4YRD9 (DNAE2_BRASO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Error-prone DNA polymerase
EC=2.7.7.7
Gene names
Name:dnaE2
Ordered Locus Names:BRADO2647
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length1170 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902

Subcellular location

Cytoplasm By similarity HAMAP MF_01902.

Sequence similarities

Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Ontologies

Keywords
   Biological processDNA damage
DNA repair
DNA replication
   Cellular componentCytoplasm
   Molecular functionDNA-directed DNA polymerase
Nucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processDNA repair

Inferred from electronic annotation. Source: UniProtKB-KW

DNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3'-5' exonuclease activity

Inferred from electronic annotation. Source: InterPro

DNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed DNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11701170Error-prone DNA polymerase HAMAP MF_01902
PRO_1000070589

Sequences

Sequence LengthMass (Da)Tools
A4YRD9 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 73C24A0B6EA41E32

FASTA1,170131,983
        10         20         30         40         50         60 
MTPIPYAEIG VTTNFSFLHG GSHPQAYVHQ AAEYGLTAIG IADHNTLAGI VRAYSELSND 

        70         80         90        100        110        120 
QLGYRPKLLY GARLVFTCGT PDILVYPRDR AAYGRLCQLL TRGKRGSDLD KVAKGDCRLA 

       130        140        150        160        170        180 
FEDLFDFIAG QLLVLMPPHR FDEDALGAIL ARLKDSPAEG VWLAGSLLYR GDDRRRLARL 

       190        200        210        220        230        240 
ARLAASAKVP LIATNDVLYH HPQQRMLQDV LTCIREKASI ESIGRRLQAN AERHLKPGHE 

       250        260        270        280        290        300 
MARLFRDHPE AIAETLRFTD RIVFSLDQLK YQYPDEPVPP GKTAQGHLED LTWAGAKTYF 

       310        320        330        340        350        360 
GDKLDDRLRA VLNKELALIA ELNYAHYFLT VHDIVRYARS EGILCQGRGS AANSAVCYVL 

       370        380        390        400        410        420 
GITSVDPTKI DLLFERFISK ERLEPPDIDV DFEHSRREEV MQYVYHRYGR HRAAIIATVI 

       430        440        450        460        470        480 
HYRPRSAIRD VGKALGLTED VTSVLADTVW GSWGDGLSDM QVRQAGLDPH NPMIRRAVEL 

       490        500        510        520        530        540 
ASELITFPRH LSQHVGGYVL TQDRLDSYVP IGNAAMDDRT FIEWDKDDVD ALSMMKVDVL 

       550        560        570        580        590        600 
ALGMLTCIRK SFDLIADHKG RRYVLSDIKS EDDNEVYQML QRGESLGVFQ VESRAQMNML 

       610        620        630        640        650        660 
PRLKPRTFYD LVIEVAIVRP GPIQGDMVHP YLRRRNKLEK VTYPSPSPDH GPSDELYKVL 

       670        680        690        700        710        720 
HKTLGVPLFQ EQAMRIAIEA AKFSPEEANG LRRAMATFRN VGTIGSYEEK MVSNMIARGY 

       730        740        750        760        770        780 
DPAFAKSCFD QIKGFGSYGF PESHAASFAQ LVYVSSWLKY FHPDAFCCAL LNSQPMGFYA 

       790        800        810        820        830        840 
PAQIVGDARK NGVEIRDIDV SHSFADNTLE KTDGEYCAVR LGFRQIDGFR WIDRDEERIR 

       850        860        870        880        890        900 
KLSEAVRKEA LSVSTRSLPA ISPVSFRGAR SANPESRDSG FALRAPRNDN DRQIPLHNDD 

       910        920        930        940        950        960 
REDDWADRII RARQRRPFTS LEDFARDTAL PKRALLLLAD ADAFRSLGLD RRAALWAVRR 

       970        980        990       1000       1010       1020 
LPDDVPLPLF EAAIAREQPD EGAQPLPEMP LPEHVVADYQ TIRLSLKGHP MEFLRRRFAA 

      1030       1040       1050       1060       1070       1080 
EGVLACRDVN DTNDRRRIRC AGVVLVRQRP GSAKGVVFMT LEDETGIANI VVWPKVMETF 

      1090       1100       1110       1120       1130       1140 
RKEVMGARLV LVEGRIQSSP EKVVHLVAER LVDRTADLTL LSDDRLDAIP HGATPAEPLN 

      1150       1160       1170 
DDRRDHTDNP SQRVSHPRNV RILPRSRDFH

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU234118 Genomic DNA. Translation: CAL76465.1.
RefSeqYP_001204702.1. NC_009445.1.

3D structure databases

ProteinModelPortalA4YRD9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4YRD9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5120654.
GenomeReviewsGene locus BRADO2647 in contig CU234118_GR.
KEGGbra:BRADO2647.
PATRIC21221485. VBIBraSp122330_2565.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0587.
HOGENOMHBG734490.
OMALATNRNG.
ProtClustDBPRK05672.

Enzyme and pathway databases

BioCycBSP376:BRADO2647-MONOMER.

Family and domain databases

HAMAPMF_01902. DNApol_error_prone.
[Tree]
InterProIPR011708. DNA_pol3_alpha.
IPR023073. DNA_pol_error_prone.
IPR004365. NA-bd_OB_tRNA-helicase.
IPR004013. PHP_C.
IPR003141. Pol/His_phosphatase_N.
IPR016195. Pol/histidinol_Pase-like.
IPR004805. PolC_alpha.
[Graphical view]
KOK14162.
PfamPF07733. DNA_pol3_alpha. 1 hit.
PF02811. PHP. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
SMARTSM00481. POLIIIAc. 1 hit.
[Graphical view]
SUPFAMSSF89550. PHP-like. 1 hit.
TIGRFAMsTIGR00594. Polc. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDNAE2_BRASO
AccessionPrimary (citable) accession number: A4YRD9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents