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A4YRC4 (A4YRC4_BRASO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH2 EMBL CAL76450.1
Synonyms:ispH1 HAMAP MF_00191
Ordered Locus Names:BRADO2632
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
A4YRC4 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 6EE326E67E373E43

FASTA32234,402
        10         20         30         40         50         60 
MADGRPLQSL LQSPLQVYLA QPRGFCAGVV RAIEIVERAL EKHGPPVYVR HEIVHNKHVV 

        70         80         90        100        110        120 
ESLKAKGAIF VEDLSEVPPR AVTVFSAHGV ARSVEEEAAA RGLPVLNATC PLVTKVHNQG 

       130        140        150        160        170        180 
KRYMAKGRTL VLIGHAGHPE VEGTMGQVPG PVHLVQNVAD VAALPLPLDT PMAYITQTTL 

       190        200        210        220        230        240 
SVDDTRDIIS ALQARFTDLQ GPDIRDICYA TQNRQSAVRD LGKLVDVILV VGAANSSNSN 

       250        260        270        280        290        300 
RLREIGTEAG IPSYLIADGR ELNPVWLKGA KAVGITAGAS APEVLVDDVI QALRRIGPVA 

       310        320 
VSVVPGREEN IEFRLPAELV AG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU234118 Genomic DNA. Translation: CAL76450.1.
RefSeqYP_001204687.1. NC_009445.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4YRC4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5120640.
GenomeReviewsGene locus BRADO2632 in contig CU234118_GR.
KEGGbra:BRADO2632.
PATRIC21221455. VBIBraSp122330_2550.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0761.
HOGENOMHBG335228.
OMAHNQGKRY.
ProtClustDBPRK01045.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4YRC4_BRASO
AccessionPrimary (citable) accession number: A4YRC4
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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