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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bradyrhizobium sp. (strain ORS278)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei166 – 1661UniRule annotation
Active sitei595 – 5951UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBSP114615:GJN5-2445-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:BRADO2580Imported
OrganismiBradyrhizobium sp. (strain ORS278)Imported
Taxonomic identifieri114615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000001994 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi114615.BRADO2580.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4YR74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLESVSMSPQ AITEEIRPNR AADVQAMEAD AQLREDIRLL GRILGDTVRD
60 70 80 90 100
QEGADVFDLV ERIRQTSVRF HRDEDRQARR ELEQILDGMT IAETVRIVRA
110 120 130 140 150
FSYFSHLANI AEDQNNIRRM RAKSDANGGA GMLAATLAHA KSAGFDAAEL
160 170 180 190 200
RKFFSTALVS PVLTAHPTEV RRKSTMDREM EVAMLLDRRE RMQLTPEERE
210 220 230 240 250
ANDEALRRAV LTLWQTNLLR RTKLTVLDEV TNGLSFYDYT FLREVPRLLC
260 270 280 290 300
SLEDRLNDGA EVAGDLASFL RMGSWIGGDR DGNPFVTAEV MRGTLKLQSS
310 320 330 340 350
LAMHYYLEEL HLLGSELSIA AHLADVSEEL RALAEKSPDT SPHRRGEPYR
360 370 380 390 400
LAVSGIYARL AATAKKLGIE ISRLPVADVA PYDSVKELQD DLDVLHHSLI
410 420 430 440 450
ANNAEVIARG RLRLLRRAVD CFGFHLARLD IRQNSAVHER TVAELIDTAM
460 470 480 490 500
PGMSYLALSE DARVGLLVNE LRNTRPLVSH FVKYSDETIG ELELFRAAAE
510 520 530 540 550
AHATFGADVI SQCIISMCKG MSDMLEVALL LKEVGLIDPS GRCAVNIVPL
560 570 580 590 600
FETIEDLQAS SGIMDRMLAL HDYRRLVDSR GAVQEVMLGY SDSNKDGGFV
610 620 630 640 650
TSGWELYKAE IHLVEIFERH HVRLRLFHGR GGSVGRGGGP SYDAIIAQPG
660 670 680 690 700
GAVNGQIRIT EQGEIISSKY SNAEVGRYNL EILAAATLEA SLLHPRQPAP
710 720 730 740 750
KREYLTAMDR LSELAFKAYR GLVYETDGFV DYFWSSTVIN EIATLNIGSR
760 770 780 790 800
PASRKKTRAI EDLRAIPWVF SWAQCRLMLP GWYGFGSAVE AWIAENPEQG
810 820 830 840 850
MPFLRELYQE WPFFRMLLSN MDMVLAKSSI AIASRYAELV PDEALREQIF
860 870 880 890 900
GRIRREWNLV IETLLDITGQ ERLLQGNPLL ERSVRNRFPY LDPLNHVQVE
910 920 930
LLKEHRAQNP DEQVLRGIQL TINGISAGLR NTG
Length:933
Mass (Da):104,734
Last modified:May 28, 2007 - v1
Checksum:i83C7572B3958730B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL76400.1.
RefSeqiWP_011925609.1. NC_009445.1.
YP_001204637.1. NC_009445.1.

Genome annotation databases

EnsemblBacteriaiCAL76400; CAL76400; BRADO2580.
KEGGibra:BRADO2580.
PATRICi21221351. VBIBraSp122330_2498.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL76400.1.
RefSeqiWP_011925609.1. NC_009445.1.
YP_001204637.1. NC_009445.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi114615.BRADO2580.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL76400; CAL76400; BRADO2580.
KEGGibra:BRADO2580.
PATRICi21221351. VBIBraSp122330_2498.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBSP114615:GJN5-2445-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ORS278Imported.

Entry informationi

Entry nameiA4YR74_BRASO
AccessioniPrimary (citable) accession number: A4YR74
Entry historyi
Integrated into UniProtKB/TrEMBL: May 28, 2007
Last sequence update: May 28, 2007
Last modified: March 31, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.