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Reviewed, UniProtKB/Swiss-Prot A4YNQ1 (ACSF_BRASO)

Last modified May 5, 2009. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase
      Short name=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase
    EC=1.14.13.81
Gene names
Name: acsF
Ordered Locus Names: BRADO1649
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

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Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity.

Catalytic activity

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Cofactor

Iron By similarity.

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the acsF family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 353353Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
PRO_1000070544

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Sequences

Sequence LengthMass (Da)Tools
A4YNQ1-1 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: F8A5BDD72FE1C2A7

FASTA35341,481
        10         20         30         40         50         60 
MIAMEGGSGN ISTKMALEDT ILTPRFYTTD FAAMDRLNVD LVRREWDAVM AELRADHNRK 

        70         80         90        100        110        120 
HFVRTPEFDK DLNELPEALR AEFKDFLVSS LTAEFSGCVL YAEIKKRITN PDIRELFQFM 

       130        140        150        160        170        180 
SRDEARHAGF INEILKDHGI GVDLGFLTKT KKYTYFKPKF IFYATYLSEK IGYARYITIY 

       190        200        210        220        230        240 
RQMERHPERQ FHPIFKWFER WCNDEFRHGE AFALLMRADP KLLSGYNKLW IKFFLLAVFA 

       250        260        270        280        290        300 
TMHVRDHMRP AFYEALGMPP DEYDMRVFRI TSEISRQVFP VMLDIDNPRF WEGLKRLREI 

       310        320        330        340        350 
SEAIAEAKAQ GGIMGTLKRA VLPLKAALTF GRLYMLPAKN NELPREIRLQ PAW

« Hide

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Cross-references

Sequence databases

CU234118 Genomic DNA. Translation: CAL75527.1.
RefSeqYP_001203764.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5118406.
GenomeReviewsGene locus BRADO1649 in contig CU234118_GR.
KEGGbra:BRADO1649.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA4YNQ1. TAEFSGC.

Family and domain databases

HAMAPMF_01840.
[Tree]
InterProIPR008434. AcsF.
IPR003251. Rubrerythrin.
[Graphical view]
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameACSF_BRASO
AccessionPrimary (citable) accession number: A4YNQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: May 5, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents