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A4YM47 (MASZ_BRASO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate synthase G
EC=2.3.3.9
Gene names
Name:glcB
Ordered Locus Names:BRADO1059
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length724 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP-Rule MF_00641

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP-Rule MF_00641

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00641

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00641.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 724724Malate synthase G HAMAP-Rule MF_00641
PRO_1000056896

Sites

Active site3381Proton acceptor By similarity
Active site6291Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A4YM47 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: A5916C8C3EBD7D52

FASTA72478,074
        10         20         30         40         50         60 
MTRIDAHGLK IAPVLFDFIT KEAAPKTGID PDAFWAGVAA ILRDLGSKNR ELLKFRDTLQ 

        70         80         90        100        110        120 
DKIDAWHLAN KGKAFDLGAY TAFLKEIGYL LPEPATQKVE TANVDDEIGK ICGPQLVVPL 

       130        140        150        160        170        180 
TNARYALNAA NARWGSLYDA FYGTDAIPHD PSEGGKGYNK ARGDKVIAKA KAFLDAAAPL 

       190        200        210        220        230        240 
ATGSHTDVTA YSVIAGQLSA KLKSGNATAL KNAGQFAGYQ GSAEAPSVIL LANNGLHVEV 

       250        260        270        280        290        300 
VIDRSHVIGK DDPAGVSDMI LEAAVSTILD MEDSVAAVDA EDKVLVYRNT LGLMNGTLSA 

       310        320        330        340        350        360 
DFEKGGKTLT RALNSDRSYT TPSGGTLALH GRSLLLIRNC GHHMFTDAVL GADGEEIPEG 

       370        380        390        400        410        420 
ILDAAVTGLL AIHDLKGHSK VKNSRTGSIY IVKPKMHGPD EVALTVELFA RVEKMLGLPE 

       430        440        450        460        470        480 
NTMKVGIMDE ERRTTVNLKA CIQQASKRIV FINTGFLDRT GDEIHTSMEA GPMIRKNEMK 

       490        500        510        520        530        540 
AQPWIKAYED WNVDMGLIDG LPGHAQIGKG MWAAPDKMAD MLAQKIGHPS AGATTAWVPS 

       550        560        570        580        590        600 
PTAATLHALH YHQVNVKARQ DELTKGGPRA KLGDILTIPV SNSNWAPDDV RQEIDNNCQG 

       610        620        630        640        650        660 
ILGYVVRWID QGVGCSKVPD IHDVGLMEDR ATLRISSQHL ANWLHHGVVS KDQVMDSLKR 

       670        680        690        700        710        720 
MAVVVDKQNA GDPLYQPMAP SFDGVAFKAA CDLVFEGRTQ PNGYTEYILT ARRREAKASE 


TAKA

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU234118 Genomic DNA. Translation: CAL74973.1.
RefSeqYP_001203210.1. NC_009445.1.

3D structure databases

ProteinModelPortalA4YM47.
SMRA4YM47. Positions 9-718.
ModBaseSearch...

Protein-protein interaction databases

STRING114615.BRADO1059.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL74973; CAL74973; BRADO1059.
GeneID5114900.
KEGGbra:BRADO1059.
PATRIC21218351. VBIBraSp122330_1004.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHOG000220740.
KOK01638.
OMAVVKPKMH.
ProtClustDBPRK02999.

Enzyme and pathway databases

BioCycBSP114615:GJN5-1011-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

Gene3D2.170.170.11. 2 hits.
HAMAPMF_00641. Malate_synth_G.
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMASZ_BRASO
AccessionPrimary (citable) accession number: A4YM47
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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