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Protein

RNA pyrophosphohydrolase

Gene

rppH

Organism
Bradyrhizobium sp. (strain ORS 278)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pyrophosphohydrolaseUniRule annotationSAAS annotation (EC:3.6.1.-UniRule annotation)
Alternative name(s):
(Di)nucleoside polyphosphate hydrolaseUniRule annotation
Gene namesi
Name:rppHUniRule annotation
Synonyms:nudHUniRule annotationImported
Ordered Locus Names:BRADO0422Imported
OrganismiBradyrhizobium sp. (strain ORS 278)Imported
Taxonomic identifieri114615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000001994 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi114615.BRADO0422.

Structurei

3D structure databases

ProteinModelPortaliA4YKE3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 162Nudix hydrolaseInterPro annotationAdd BLAST153

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi51 – 72Nudix boxUniRule annotationAdd BLAST22

Sequence similaritiesi

Belongs to the Nudix hydrolase family. RppH subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105EJF. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000066722.
KOiK08311.
OMAiPLDCVIE.
OrthoDBiPOG091H0392.

Family and domain databases

CDDicd03671. Ap4A_hydrolase_plant_like. 1 hit.
HAMAPiMF_00298. Nudix_RppH. 1 hit.
InterProiView protein in InterPro
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR022927. RppH.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

A4YKE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDASMTETRP YRPNVGIALL NADGLVFLGR RFRDDGPEIV LPGLEWQMPQ
60 70 80 90 100
GGVDAGEDLQ AAARRELWEE TGIRDADILA ETDWLTYEFP PFEDPNHRLA
110 120 130 140 150
RFRGQRQKWF AMRFTGREAD IDPVTPRNGQ PAEFDAWRWE RLARVPDLVV
160
PFRREVYRAV AEAFAHLAA
Length:169
Mass (Da):19,453
Last modified:May 29, 2007 - v1
Checksum:iC3C6C5E1CF0D7D1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU234118 Genomic DNA. Translation: CAL74369.1.

Genome annotation databases

EnsemblBacteriaiCAL74369; CAL74369; BRADO0422.
KEGGibra:BRADO0422.

Similar proteinsi

Entry informationi

Entry nameiA4YKE3_BRASO
AccessioniPrimary (citable) accession number: A4YKE3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: August 30, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported