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A4YK54 (PNCB_BRASO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BRADO0323
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146834

Sequences

Sequence LengthMass (Da)Tools
A4YK54 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 23B98C80298AFC4D

FASTA43449,506
        10         20         30         40         50         60 
MTVTDIASRT YNHGWRLDPI VRSLLDTDFY KLLMLQMIRE FYPDQKVTFS VINRTKRVRL 

        70         80         90        100        110        120 
GDVIDEGELR AQLDHARTIR FSKKELIWLA GNTFYGKTHM FSPDFLAWLA NFRLPEYELH 

       130        140        150        160        170        180 
KADGQYELHF HGLWTHTTMW EIPALAIVNE LRSRQAMKGQ GRFALDVLFA RAKAKLWAKV 

       190        200        210        220        230        240 
ERLRKLEGLR LSDFGTRRRH GFLWQRWCVE AVKEGLGSSF TGTSNVLLAM DNDLEAIGTN 

       250        260        270        280        290        300 
AHELPMVAAA LAKDDDELRF APYRILDQWR QTYAGNLLIA LPDAFGTKAF LRDAPDWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIQAGEEIIA WWKSKGRDPR QKLLVFSDAM DVESIEQIHQ RFSDQVRLSF 

       370        380        390        400        410        420 
GWGTNLTNDF VGCSPDGSVD LDPISLVCKV TSVDGRPAVK LSDNPEKATG DPAEIARYLR 

       430 
VFGDAGRVRT PVFV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU234118 Genomic DNA. Translation: CAL74280.1.
RefSeqYP_001202526.1. NC_009445.1.

3D structure databases

ProteinModelPortalA4YK54.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING114615.BRADO0323.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL74280; CAL74280; BRADO0323.
GeneID5116171.
KEGGbra:BRADO0323.
PATRIC21216962. VBIBraSp122330_0314.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBSP114615:GJN5-312-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BRASO
AccessionPrimary (citable) accession number: A4YK54
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways