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A4YJR3 (RNPH_BRASO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease PH

Short name=RNase PH
EC=2.7.7.56
Alternative name(s):
tRNA nucleotidyltransferase
Gene names
Name:rph
Ordered Locus Names:BRADO0173
OrganismBradyrhizobium sp. (strain ORS278) [Complete proteome] [HAMAP]
Taxonomic identifier114615 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP-Rule MF_00564

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP-Rule MF_00564

Sequence similarities

Belongs to the RNase PH family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA nucleotidyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA-specific ribonuclease activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Ribonuclease PH HAMAP-Rule MF_00564
PRO_1000024779

Sequences

Sequence LengthMass (Da)Tools
A4YJR3 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: E32EE9FC3816BA9A

FASTA23725,930
        10         20         30         40         50         60 
MRPSRRAPDE MRAVSLERGV VKYAEGSCLV KFGDTHVLVT ATLEDRLPPW LKGQGRGWIT 

        70         80         90        100        110        120 
AEYGMLPRAT LERTRREASA GKQTGRTVEI QRLIGRSLRT AIDLEALGER QITVDCDVLQ 

       130        140        150        160        170        180 
ADGGTRTASI TGAWVALADC IRWMKARNMI KTEVLRTNVA AVSCGIYNGT PVLDLDYAED 

       190        200        210        220        230 
SEAETDANFV MTGDGRIIEV QGTAEKTPFS EAEFLALMAL ARKGVGRLVD LQKMAVA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU234118 Genomic DNA. Translation: CAL74139.1.
RefSeqYP_001202389.1. NC_009445.1.

3D structure databases

ProteinModelPortalA4YJR3.
SMRA4YJR3. Positions 2-236.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING114615.BRADO0173.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL74139; CAL74139; BRADO0173.
GeneID5121098.
KEGGbra:BRADO0173.
PATRIC21216672. VBIBraSp122330_0172.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0689.
HOGENOMHOG000229516.
KOK00989.
OMAKGQGWVT.
OrthoDBEOG6CZQQP.
ProtClustDBPRK00173.

Enzyme and pathway databases

BioCycBSP114615:GJN5-168-MONOMER.

Family and domain databases

Gene3D3.30.230.70. 1 hit.
HAMAPMF_00564. RNase_PH.
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPH_BRASO
AccessionPrimary (citable) accession number: A4YJR3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families