Reviewed, UniProtKB/Swiss-Prot A4YIX4 (APGM_METS5)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Msed_2238

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]

Taxonomic identifier

399549 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 413	413	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000073505

Sequences

	Sequence		Length	Mass (Da)
	A4YIX4-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 21C3491B15C8BEDF	FASTA	413	44,562
	10 20 30 40 50 60 MKKYKILLVI GDGLGDRQVA SLNGRTPLEN ADKPTIASLL RSSLVGLMDP IGPGIVPGSD 70 80 90 100 110 120 TSHLAIFGLD PKKYYKGRGS FEALGAGAIL TEGDIAFRGN FATVDSNLVV IDRRAGRKIE 130 140 150 160 170 180 EAEDLVKELN DKIQEIDGVK VRFYHGTEHR VSVVLSGDNL SDKVSDTDPH EVGKRILNSE 190 200 210 220 230 240 PTDDALSSKR TANIINALTR RIYEVLSNSQ LNDKRVREGL PPANIVLLRG ASIHTELPKL 250 260 270 280 290 300 KDYTGLSGAA VSATALIKGV CKSLGMEVVT PPGATGGIDT DYMAKAEAAA KLLEDHDLVF 310 320 330 340 350 360 LHIKATDAAS HDGKVSEKVK AIEMIDRSIG RVLDRYGSEL VVLFTGDHAT PVELREHSGD 370 380 390 400 410 PVPLMLYVPT NIIPDNVGDF NERQARKGSL KITGLNIIDL LLNFSNRATK YGA

References

[1]

"Complete sequence of Metallosphaera sedula DSM 5348." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Han C., Detter J.C., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Maezato Y., Auernik K.S., Kelly R.M., Blum P., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000682 Genomic DNA. Translation: ABP96376.1.
RefSeq	YP_001192300.1.
3D structure databases
SMR	A4YIX4. Positions 282-369.
ModBase	Search...
Protein-protein interaction databases
STRING	A4YIX4.
Genome annotation databases
GeneID	5104299.
GenomeReviews	Gene locus Msed_2238 in contig CP000682_GR.
KEGG	mse:Msed_2238.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
OMA	ITGDHST.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017850. Alkaline_phosphatase_core. IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METS5

Accession

Primary (citable) accession number: A4YIX4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	May 29, 2007
Last modified:	February 9, 2010
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)