A4YI72 (A4YI72_METS5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Msed_1984

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]

Taxonomic identifier

399549 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ABP96124.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4YI72 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: F5709DBF04BAADE5	FASTA	323	35,244
	10 20 30 40 50 60 MVSEYKDAGV DLNKLKEIHR DIASAISSTY RRTVLGAGHY SGVVEINGLK LAIHVDGVGT 70 80 90 100 110 120 KVILAKRARK YRSVGIDCVA MNVNDLISIG AKPIALVDYI AMDQPSEEVI SEIVQGLVQG 130 140 150 160 170 180 AKESDTEIVG GETAAMKDVV NGFDLSCTAL GVVDKLKTGE EVSPGDVIIG LASNGVHANG 190 200 210 220 230 240 YSLVRKLLDE GKLSWKDWEE ELLKPTRIYV KPVLEVLELI KAAGHITGGS FSKLRRITNY 250 260 270 280 290 300 SLELTLPDPP LIFKTIEQAG ISHEEMHRVF NMGIGMVVFV DRTNAEDVLR KLNPYVPSQI 310 320 IGEVKDNVGQ IKITTYKSQV LYL

References

[1]

"The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism." Auernik K.S., Maezato Y., Blum P.H., Kelly R.M. Appl. Environ. Microbiol. 74:682-692(2008) [PubMed: 18083856] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000682 Genomic DNA. Translation: ABP96124.1.
RefSeq	YP_001192048.1. NC_009440.1.
3D structure databases
ProteinModelPortal	A4YI72.
ModBase	Search...
Protein-protein interaction databases
STRING	A4YI72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5103371.
GenomeReviews	Gene locus Msed_1984 in contig CP000682_GR.
KEGG	mse:Msed_1984.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	GIDMIAM.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4YI72_METS5

Accession

Primary (citable) accession number: A4YI72

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	November 16, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)