A4YI54 (A4YI54_METS5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Orotidine-5'-phosphate decarboxylase EMBL ABP96106.1
EC=4.1.1.23 EMBL ABP96106.1

Gene names

Ordered Locus Names:

Msed_1966

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]

Taxonomic identifier

399549 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera › Metallosphaera sedula

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Lyase EMBL ABP96106.1
Technical term	3D-structure PDB 3VE7 PDB 3VE9 Complete proteome
Gene Ontology (GO)
Biological_process	'de novo' pyrimidine nucleobase biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	orotidine-5'-phosphate decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4YI54 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: F7D9C7A64F668DCD	FASTA	215	23,404
	10 20 30 40 50 60 MNRVILSLDS PIPEETLRKL NGKVAGIKVG WPLLLNLGKE KVKELVGLVD GIKILDLKLA 70 80 90 100 110 120 DIDNTMILIV DELKDITNSF IAHAFVGVEG SLASLSQRVD LFLVLSMSHP GWNDAFYPYL 130 140 150 160 170 180 REVARRVNPK GFVAPATRPS MISRVKGDFP DKLVISPGVG TQGAKPGIAL CHGADYEIVG 190 200 210 RSVYQSADPV RKLEEIVRSQ EEVLSSCEGA KDRGS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism." Auernik K.S., Maezato Y., Blum P.H., Kelly R.M. Appl. Environ. Microbiol. 74:682-692(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51363 / DSM 5348.
[2]	"Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula complexed with inhibitor BMP." Fedorov A.A., Fedorov E.V., Desai B., Gerlt J.A., Almo S.C. Submitted (JAN-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.54 ANGSTROMS).
[3]	"Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula." Fedorov A.A., Fedorov E.V., Desai B., Gerlt J.A., Almo S.C. Submitted (JAN-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000682 Genomic DNA. Translation: ABP96106.1.

RefSeq

YP_001192030.1. NC_009440.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3VE7	X-ray	1.54	A/B	1-215	[»]
3VE9	X-ray	1.45	A/B	1-215	[»]

ProteinModelPortal

A4YI54.

ModBase

Search...

Protein-protein interaction databases

STRING

399549.Msed_1966.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABP96106; ABP96106; Msed_1966.

GeneID

5103353.

KEGG

mse:Msed_1966.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG0284.

HOGENOM

HOG000226069.

KO

K01591.

OMA

TEMSHPG.

ProtClustDB

CLSK802793.

Enzyme and pathway databases

BioCyc

MSED399549:GH1O-1997-MONOMER.

Family and domain databases

Gene3D

3.20.20.70. 1 hit.

InterPro

IPR013785. Aldolase_TIM.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]

Pfam

PF00215. OMPdecase. 1 hit.
[Graphical view]

SMART

SM00934. OMPdecase. 1 hit.
[Graphical view]

SUPFAM

SSF51366. RibP_bind_barrel. 1 hit.

ProtoNet

Search...

Entry information

Entry name

A4YI54_METS5

Accession

Primary (citable) accession number: A4YI54

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	May 29, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)