A4YHB6 (A4YHB6_METS5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Ordered Locus Names:

Msed_1663

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]

Taxonomic identifier

399549 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 Methyltransferase EMBL ABP95818.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4YHB6 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: E175CE335B7613C1	FASTA	347	39,062
	10 20 30 40 50 60 MFWTPLINFE EKLGANLGEF AGWKMPMTYT SYQEEHMAVR TKSAFFDLSH MGRLRITGKL 70 80 90 100 110 120 QEFENLVAKK VSDSSPGTMV GPTAFLNDKA GFVDDVMTYK VSESEFLVVT NAINREKVIN 130 140 150 160 170 180 WIRKNSSLEV EDLTFDLVMI ALQGRGIWEV AEKPDLSPLQ FKLNAKFEGH EVFLLSRSGW 190 200 210 220 230 240 TGEDGLEFWA KPEVAQSILE RLIARGVKGA GLVARDSLRQ EMGFVLYGED IGEDVNPVEA 250 260 270 280 290 300 RYWVYSLDKD FIGKGALLDI LRTGVDRLRI GIKLPKNQRV IPRNSSKIKI AGKEVGYVTS 310 320 330 340 STFSPYLSRV IGMGYLSSRH FLMGGNAEVE VRGKDYSVKL SDFPLFK

References

[1]

"The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism." Auernik K.S., Maezato Y., Blum P.H., Kelly R.M. Appl. Environ. Microbiol. 74:682-692(2008) [PubMed: 18083856] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000682 Genomic DNA. Translation: ABP95818.1.
RefSeq	YP_001191742.1. NC_009440.1.
3D structure databases
ProteinModelPortal	A4YHB6.
ModBase	Search...
Protein-protein interaction databases
STRING	A4YHB6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5104868.
GenomeReviews	Gene locus Msed_1663 in contig CP000682_GR.
KEGG	mse:Msed_1663.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG06551.
HOGENOM	HBG299834.
OMA	GWEMPIS.
ProtClustDB	PRK00389.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4YHB6_METS5

Accession

Primary (citable) accession number: A4YHB6

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)