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A4YES9

- CAPPA_METS5

UniProt

A4YES9 - CAPPA_METS5

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BioCyciMSED399549:GH1O-771-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:Msed_0756
    OrganismiMetallosphaera sedula (strain ATCC 51363 / DSM 5348)
    Taxonomic identifieri399549 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
    ProteomesiUP000000242: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 509509Phosphoenolpyruvate carboxylasePRO_1000088478Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi399549.Msed_0756.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1892.
    HOGENOMiHOG000038601.
    KOiK01595.
    OMAiKTMSTQH.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4YES9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRPIPRTMST QHPDNATVPE WAKGDVIEGE AEVIEAYYAF SRLNVHEVMW    50
    DAEGKDVDTH VVRKLFSSFD EYFKNNILGE DIFLTYRLPN PKIEGAERKV 100
    FAETMESIPI TFDVAERFYG RKVVPVFEVI LPFTTNASDI ISVARYYERA 150
    VAMEENIELQ DGVYVRDLVG EIYPKRIEVI PLIEDKDSLL NTRNIIEGYY 200
    RAIKPSYMRL FIARSDPAMN YGMLTAVLLA KYALSEAGKL AEELGIPIFP 250
    IIGVGSLPFR GHLSPENYQR VMEEYEGVYT FTIQSAFKYD YSEEQVKGAI 300
    SHINREEVKE PRILGEEEKK VTRDIIETYT LSYQPVIESL ANLINTVALH 350
    LPRRRARKLH ISLFGYARST GKVMLPRAIT FVGSLYSVGL PPEVIGISSL 400
    GKLNEMQWNI LEENYKFLKN DLQKASEFIN PEGLSTLVSY GYLDAEISKK 450
    LEEDIKYLES MGVKIGPRSY ETKKHALLSQ LLMLSLKEKK YNEVKQYARE 500
    MAVIRKSIG 509
    Length:509
    Mass (Da):58,245
    Last modified:May 29, 2007 - v1
    Checksum:iFCF967A96862D3C5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94931.1.
    RefSeqiYP_001190855.1. NC_009440.1.

    Genome annotation databases

    EnsemblBacteriaiABP94931; ABP94931; Msed_0756.
    GeneIDi5103445.
    KEGGimse:Msed_0756.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94931.1 .
    RefSeqi YP_001190855.1. NC_009440.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399549.Msed_0756.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP94931 ; ABP94931 ; Msed_0756 .
    GeneIDi 5103445.
    KEGGi mse:Msed_0756.

    Phylogenomic databases

    eggNOGi COG1892.
    HOGENOMi HOG000038601.
    KOi K01595.
    OMAi KTMSTQH.

    Enzyme and pathway databases

    BioCyci MSED399549:GH1O-771-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism."
      Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.
      Appl. Environ. Microbiol. 74:682-692(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51363 / DSM 5348.

    Entry informationi

    Entry nameiCAPPA_METS5
    AccessioniPrimary (citable) accession number: A4YES9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3