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A4YEM6

- A4YEM6_METS5

UniProt

A4YEM6 - A4YEM6_METS5

Protein
Submitted name:

Isocitrate dehydrogenase (NADP)

Gene

Msed_0703

Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Enzyme and pathway databases

    BioCyciMSED399549:GH1O-717-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase (NADP)Imported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Msed_0703Imported
    OrganismiMetallosphaera sedula (strain ATCC 51363 / DSM 5348)Imported
    Taxonomic identifieri399549 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
    ProteomesiUP000000242: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi399549.Msed_0703.

    Structurei

    3D structure databases

    ProteinModelPortaliA4YEM6.
    SMRiA4YEM6. Positions 24-430.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR001804. Isocitrate/isopropylmalate_DH.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4YEM6-1 [UniParc]FASTAAdd to Basket

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    MSEPLIIQKV KSCSNYLTFM SHVPDDGEKI SFQNGRWIVP NKPVILYIEG    50
    DGIGPEIVTS ARQVVDKAVE KAYGSKREIK WVEVLAGDKA FAKTGDRFPK 100
    ETQEMLLNYR VVVKGPLETP IGKGWKSVNV AIRLMLDLYA NIRPVKYIDG 150
    LESPLKEPNK VDMIIFRENT DDLYRGIEYT YDSEEAKKIR SFLKNELHVD 200
    VEDDTGIGIK VISKFKTERI TRMAMNYAIE HGRRKLTIMH KGNVLKYTEG 250
    AFRDWAYDLI KREYRDKVVT EEEIMKDYNG KAPEGKIVVN DRIADNMFQQ 300
    IITRPDEYDV ILAPNLNGDY ISDAAGALIG NIGMLGGANI GDSGGMFEAI 350
    HGTAPKYAGK NMANPTGIIK GCELMLRFMG WNEAADLVEK SVLRAVSAKR 400
    VTQDLARFMG VKALSTTEFT KELINIMDTL 430
    Length:430
    Mass (Da):48,395
    Last modified:May 29, 2007 - v1
    Checksum:iC1D3B0A8B288115C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94878.1.
    RefSeqiYP_001190802.1. NC_009440.1.

    Genome annotation databases

    EnsemblBacteriaiABP94878; ABP94878; Msed_0703.
    GeneIDi5105309.
    KEGGimse:Msed_0703.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94878.1 .
    RefSeqi YP_001190802.1. NC_009440.1.

    3D structure databases

    ProteinModelPortali A4YEM6.
    SMRi A4YEM6. Positions 24-430.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399549.Msed_0703.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP94878 ; ABP94878 ; Msed_0703 .
    GeneIDi 5105309.
    KEGGi mse:Msed_0703.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.

    Enzyme and pathway databases

    BioCyci MSED399549:GH1O-717-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR001804. Isocitrate/isopropylmalate_DH.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism."
      Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.
      Appl. Environ. Microbiol. 74:682-692(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51363 / DSM 5348Imported.

    Entry informationi

    Entry nameiA4YEM6_METS5
    AccessioniPrimary (citable) accession number: A4YEM6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 29, 2007
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3