Reviewed, UniProtKB/Swiss-Prot A4YEM3 (PHS_METS5)

Names and origin

Protein names

Recommended name:
    Putative pterin-4-alpha-carbinolamine dehydratase
      Short name=PHS
    EC=4.2.1.96
Alternative name(s):
    4-alpha-hydroxy-tetrahydropterin dehydratase
    Pterin carbinolamine dehydratase
      Short name=PCD

Gene names

Ordered Locus Names:

Msed_0700

Organism

Metallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]

Taxonomic identifier

399549 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000072315

Sequences

	Sequence		Length	Mass (Da)
	A4YEM3-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 713B0E3BB1B83100	FASTA	96	11,181
	10 20 30 40 50 60 MPRLSVQEID QALKGLRNWR FENGELVKEF KFADFDSSIR FLNMVQPVAD SLDHHPDLCV 70 80 90 YYNRVIVHLT THDEGGVTDL DLKLAQKLDE LEKMVH

References

[1]

"Complete sequence of Metallosphaera sedula DSM 5348." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Han C., Detter J.C., Bruce D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Maezato Y., Auernik K.S., Kelly R.M., Blum P., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000682 Genomic DNA. Translation: ABP94875.1.
RefSeq	YP_001190799.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4YEM3.
Genome annotation databases
GeneID	5105306.
GenomeReviews	Gene locus Msed_0700 in contig CP000682_GR.
KEGG	mse:Msed_0700.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NEKAIIR.
Family and domain databases
HAMAP	MF_00434. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
ProDom	PD007262. Trans_pterinDh. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

PHS_METS5

Accession

Primary (citable) accession number: A4YEM3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	May 29, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)