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A4YEI1 (IF2B_METS5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 2 subunit beta
Alternative name(s):
aIF2-beta
eIF-2-beta
Gene names
Name:eif2b
Ordered Locus Names:Msed_0658
OrganismMetallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]
Taxonomic identifier399549 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera

Protein attributes

Sequence length140 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity. HAMAP-Rule MF_00232

Subunit structure

Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.

Sequence similarities

Belongs to the eIF-2-beta/eIF-5 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 140140Translation initiation factor 2 subunit beta HAMAP-Rule MF_00232
PRO_0000336756

Sequences

Sequence LengthMass (Da)Tools
A4YEI1 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: CABC0330B51B4EB0

FASTA14016,030
        10         20         30         40         50         60 
MSERDKLYHV LLDRLYAKLP KKDLASETQT LPTLSIINVG NTTIIRNFSE YCDRIRREDK 

        70         80         90        100        110        120 
ICMRYLLKEL AAAGSISENG QLMIQGKFSN AIVNTFMDRF LKTYVQCSTC KSLDTVLVKD 

       130        140 
KKIWYIQCLA CGAKNPVKPL 

« Hide

References

[1]"The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism."
Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.
Appl. Environ. Microbiol. 74:682-692(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51363 / DSM 5348.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000682 Genomic DNA. Translation: ABP94833.1.
RefSeqYP_001190757.1. NC_009440.1.

3D structure databases

ProteinModelPortalA4YEI1.
SMRA4YEI1. Positions 8-140.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING399549.Msed_0658.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP94833; ABP94833; Msed_0658.
GeneID5103818.
KEGGmse:Msed_0658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1601.
HOGENOMHOG000107197.
KOK03238.
OMADTKIIKR.

Enzyme and pathway databases

BioCycMSED399549:GH1O-672-MONOMER.

Family and domain databases

Gene3D3.30.30.50. 1 hit.
HAMAPMF_00232. eIF_2_beta.
InterProIPR004458. TIF2_bsu_arc.
IPR002735. Transl_init_fac_IF2/IF5.
IPR016189. Transl_init_fac_IF2/IF5_N.
IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
[Graphical view]
PfamPF01873. eIF-5_eIF-2B. 1 hit.
[Graphical view]
SUPFAMSSF100966. SSF100966. 1 hit.
SSF75689. SSF75689. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF2B_METS5
AccessionPrimary (citable) accession number: A4YEI1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries