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A4YEI1

- IF2B_METS5

UniProt

A4YEI1 - IF2B_METS5

Protein

Translation initiation factor 2 subunit beta

Gene

eif2b

Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciMSED399549:GH1O-672-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor 2 subunit betaUniRule annotation
    Alternative name(s):
    aIF2-betaUniRule annotation
    eIF-2-betaUniRule annotation
    Gene namesi
    Name:eif2bUniRule annotation
    Ordered Locus Names:Msed_0658
    OrganismiMetallosphaera sedula (strain ATCC 51363 / DSM 5348)
    Taxonomic identifieri399549 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
    ProteomesiUP000000242: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 140140Translation initiation factor 2 subunit betaPRO_0000336756Add
    BLAST

    Interactioni

    Subunit structurei

    Heterotrimer composed of an alpha, a beta and a gamma chain.UniRule annotation

    Protein-protein interaction databases

    STRINGi399549.Msed_0658.

    Structurei

    3D structure databases

    ProteinModelPortaliA4YEI1.
    SMRiA4YEI1. Positions 8-140.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eIF-2-beta/eIF-5 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1601.
    HOGENOMiHOG000107197.
    KOiK03238.
    OMAiDTKIIKR.

    Family and domain databases

    Gene3Di3.30.30.50. 1 hit.
    HAMAPiMF_00232. eIF_2_beta.
    InterProiIPR004458. TIF2_bsu_arc.
    IPR002735. Transl_init_fac_IF2/IF5.
    IPR016189. Transl_init_fac_IF2/IF5_N.
    IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
    [Graphical view]
    PfamiPF01873. eIF-5_eIF-2B. 1 hit.
    [Graphical view]
    SUPFAMiSSF100966. SSF100966. 1 hit.
    SSF75689. SSF75689. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4YEI1-1 [UniParc]FASTAAdd to Basket

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    MSERDKLYHV LLDRLYAKLP KKDLASETQT LPTLSIINVG NTTIIRNFSE    50
    YCDRIRREDK ICMRYLLKEL AAAGSISENG QLMIQGKFSN AIVNTFMDRF 100
    LKTYVQCSTC KSLDTVLVKD KKIWYIQCLA CGAKNPVKPL 140
    Length:140
    Mass (Da):16,030
    Last modified:May 29, 2007 - v1
    Checksum:iCABC0330B51B4EB0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94833.1.
    RefSeqiYP_001190757.1. NC_009440.1.

    Genome annotation databases

    EnsemblBacteriaiABP94833; ABP94833; Msed_0658.
    GeneIDi5103818.
    KEGGimse:Msed_0658.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000682 Genomic DNA. Translation: ABP94833.1 .
    RefSeqi YP_001190757.1. NC_009440.1.

    3D structure databases

    ProteinModelPortali A4YEI1.
    SMRi A4YEI1. Positions 8-140.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399549.Msed_0658.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP94833 ; ABP94833 ; Msed_0658 .
    GeneIDi 5103818.
    KEGGi mse:Msed_0658.

    Phylogenomic databases

    eggNOGi COG1601.
    HOGENOMi HOG000107197.
    KOi K03238.
    OMAi DTKIIKR.

    Enzyme and pathway databases

    BioCyci MSED399549:GH1O-672-MONOMER.

    Family and domain databases

    Gene3Di 3.30.30.50. 1 hit.
    HAMAPi MF_00232. eIF_2_beta.
    InterProi IPR004458. TIF2_bsu_arc.
    IPR002735. Transl_init_fac_IF2/IF5.
    IPR016189. Transl_init_fac_IF2/IF5_N.
    IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
    [Graphical view ]
    Pfami PF01873. eIF-5_eIF-2B. 1 hit.
    [Graphical view ]
    SUPFAMi SSF100966. SSF100966. 1 hit.
    SSF75689. SSF75689. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism."
      Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.
      Appl. Environ. Microbiol. 74:682-692(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51363 / DSM 5348.

    Entry informationi

    Entry nameiIF2B_METS5
    AccessioniPrimary (citable) accession number: A4YEI1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3