Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translation initiation factor 2 subunit beta

Gene

eif2b

Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 2 subunit betaUniRule annotation
Alternative name(s):
aIF2-betaUniRule annotation
eIF-2-betaUniRule annotation
Gene namesi
Name:eif2bUniRule annotation
Ordered Locus Names:Msed_0658
OrganismiMetallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Taxonomic identifieri399549 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
Proteomesi
  • UP000000242 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003367561 – 140Translation initiation factor 2 subunit betaAdd BLAST140

Interactioni

Subunit structurei

Heterotrimer composed of an alpha, a beta and a gamma chain.UniRule annotation

Protein-protein interaction databases

STRINGi399549.Msed_0658

Structurei

3D structure databases

ProteinModelPortaliA4YEI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-2-beta/eIF-5 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01640 Archaea
COG1601 LUCA
HOGENOMiHOG000107197
KOiK03238
OMAiFIRYYVV
OrthoDBiPOG093Z0DYX

Family and domain databases

HAMAPiMF_00232 eIF_2_beta, 1 hit
InterProiView protein in InterPro
IPR004458 TIF2_bsu_arc
IPR002735 Transl_init_fac_IF2/IF5
IPR016189 Transl_init_fac_IF2/IF5_N
IPR016190 Transl_init_fac_IF2/IF5_Zn-bd
PfamiView protein in Pfam
PF01873 eIF-5_eIF-2B, 1 hit
SMARTiView protein in SMART
SM00653 eIF2B_5, 1 hit
SUPFAMiSSF100966 SSF100966, 1 hit
SSF75689 SSF75689, 1 hit

Sequencei

Sequence statusi: Complete.

A4YEI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSERDKLYHV LLDRLYAKLP KKDLASETQT LPTLSIINVG NTTIIRNFSE
60 70 80 90 100
YCDRIRREDK ICMRYLLKEL AAAGSISENG QLMIQGKFSN AIVNTFMDRF
110 120 130 140
LKTYVQCSTC KSLDTVLVKD KKIWYIQCLA CGAKNPVKPL
Length:140
Mass (Da):16,030
Last modified:May 29, 2007 - v1
Checksum:iCABC0330B51B4EB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000682 Genomic DNA Translation: ABP94833.1
RefSeqiWP_012020620.1, NC_009440.1

Genome annotation databases

EnsemblBacteriaiABP94833; ABP94833; Msed_0658
GeneIDi5103818
KEGGimse:Msed_0658

Similar proteinsi

Entry informationi

Entry nameiIF2B_METS5
AccessioniPrimary (citable) accession number: A4YEI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health