Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4YD90 (A4YD90_METS5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Ordered Locus Names:Msed_0215
OrganismMetallosphaera sedula (strain ATCC 51363 / DSM 5348) [Complete proteome] [HAMAP]
Taxonomic identifier399549 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Metallosphaera

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2021Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2551Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding2401Magnesium By similarity PIRSR PIRSR001415-5
Binding site2121Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2241Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2821Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3211Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
A4YD90 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 3A29FEF881BE16A7

FASTA33637,677
        10         20         30         40         50         60 
MVGYPKIRPR RLRQNKNIRD AVAETKLTHD NLILPIFVKE GISKPEEISS MPDVYRYPVG 

        70         80         90        100        110        120 
DPLIKFVEGN YSKGIRKVIL FGIPSFKDNI ASSAYQKDGV IQRSLKLLKE TFGDKILLFA 

       130        140        150        160        170        180 
DECTDEYTSH GHCGIVNYRG KQYYIDNDES LKVHAKIALS QAEAGADVIA PSSMMDGVVG 

       190        200        210        220        230        240 
AIREELDRNG FTDTLIMSYS VKYASVFYSP FREAASSAPA FGDRKSYQMD PRNANEAIKE 

       250        260        270        280        290        300 
ARLDLEEGAD ILMVKPAHTY LDVIRLVKET YPEYPLAAYH VSGEYSMIKA AAINGWLNEK 

       310        320        330 
VAVLEITHAI RRAGADMILT YYAPKLAEWI LEASPF

« Hide

References

[1]"The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism."
Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.
Appl. Environ. Microbiol. 74:682-692(2008) [PubMed: 18083856] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000682 Genomic DNA. Translation: ABP94392.1.
RefSeqYP_001190316.1. NC_009440.1.

3D structure databases

ProteinModelPortalA4YD90.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4YD90.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5104081.
GenomeReviewsGene locus Msed_0215 in contig CP000682_GR.
KEGGmse:Msed_0215.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05029.
HOGENOMHBG285270.
OMAHCGVVEN.
PhylomeDBA4YD90.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4YD90_METS5
AccessionPrimary (citable) accession number: A4YD90
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info