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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:Msed_0207
OrganismiMetallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Taxonomic identifieri399549 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeMetallosphaera
Proteomesi
  • UP000000242 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000726591 – 117Peptidyl-tRNA hydrolaseAdd BLAST117

Interactioni

Protein-protein interaction databases

STRINGi399549.Msed_0207

Structurei

3D structure databases

ProteinModelPortaliA4YD82
SMRiA4YD82
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04228 Archaea
COG1990 LUCA
HOGENOMiHOG000227349
KOiK04794
OMAiKQVIVVR
OrthoDBiPOG093Z0KDX

Family and domain databases

CDDicd02430 PTH2, 1 hit
Gene3Di3.40.1490.101 hit
HAMAPiMF_00628 Pept_tRNA_hydro_arch, 1 hit
InterProiView protein in InterPro
IPR023476 Pep_tRNA_hydro_II_dom_sf
IPR034759 Pept_tRNA_hydro_arch
IPR002833 PTH2
PfamiView protein in Pfam
PF01981 PTH2, 1 hit
SUPFAMiSSF102462 SSF102462, 1 hit
TIGRFAMsiTIGR00283 arch_pth2, 1 hit

Sequencei

Sequence statusi: Complete.

A4YD82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMVVMVRTD INMGKGKIAA QVAHAAVSLV LDCMSRSSWR DWLDSWLHEG
60 70 80 90 100
QPKVVVKVSS LEDLLSRVDK ARSQGLPTTV ISDAGRTQVE PGTVTCAGIG
110
PGPDDLIDKI TGDLKLL
Length:117
Mass (Da):12,584
Last modified:May 29, 2007 - v1
Checksum:i7936EA406B1EBC80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000682 Genomic DNA Translation: ABP94384.1
RefSeqiWP_011921352.1, NC_009440.1

Genome annotation databases

EnsemblBacteriaiABP94384; ABP94384; Msed_0207
GeneIDi5104073
KEGGimse:Msed_0207

Similar proteinsi

Entry informationi

Entry nameiPTH_METS5
AccessioniPrimary (citable) accession number: A4YD82
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 29, 2007
Last modified: November 22, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome