ID   A4YBG1_SHEPC            Unreviewed;       804 AA.
AC   A4YBG1;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=Adenylate cyclase {ECO:0000256|ARBA:ARBA00021420};
DE            EC=4.6.1.1 {ECO:0000256|ARBA:ARBA00012201};
DE   AltName: Full=ATP pyrophosphate-lyase {ECO:0000256|ARBA:ARBA00032597};
DE   AltName: Full=Adenylyl cyclase {ECO:0000256|ARBA:ARBA00032637};
GN   OrderedLocusNames=Sputcn32_3586 {ECO:0000313|EMBL:ABP77294.1};
OS   Shewanella putrefaciens (strain CN-32 / ATCC BAA-453).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=319224 {ECO:0000313|EMBL:ABP77294.1};
RN   [1] {ECO:0000313|EMBL:ABP77294.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CN-32 {ECO:0000313|EMBL:ABP77294.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Fredrickson J.,
RA   Tiedje J., Richardson P.;
RT   "Complete sequence of Shewanella putrefaciens CN-32.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP = 3',5'-cyclic AMP + diphosphate; Xref=Rhea:RHEA:15389,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58165; EC=4.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001593};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-1 family.
CC       {ECO:0000256|ARBA:ARBA00007901, ECO:0000256|RuleBase:RU004184}.
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DR   EMBL; CP000681; ABP77294.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4YBG1; -.
DR   STRING; 319224.Sputcn32_3586; -.
DR   KEGG; spc:Sputcn32_3586; -.
DR   eggNOG; COG3072; Bacteria.
DR   HOGENOM; CLU_013280_0_0_6; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024686; Adenylate_cyclase_1_CS.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
DR   PIRSF; PIRSF001444; Adenylate_cycl; 2.
DR   PROSITE; PS01092; ADENYLATE_CYCLASE_1_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   cAMP biosynthesis {ECO:0000256|ARBA:ARBA00022998};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          10..202
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   804 AA;  92659 MW;  D0DF4A1500DF17E0 CRC64;
     MDQQDLFPDI AERLNEVRIA RALALLSPLQ KHLFHLIPFL IHQNSVQYPG YHHPNTPSGI
     SGYKEGKNAS LACDVFKLPF IPQEMDTYAF EGVYAMGSTA SFGQNVKSDV DVWLVHHPQL
     CDEDLALIRT KANRLTAWFA DYHFEVNFYL VHPQQFSGGQ KGRSACQASM AHEHSGSTQH
     WLLLEEFYRS QIRLAGKTIA WWPNAKLNPD LLYLGDVHEL PASEYFGASL WQLYKGLNKP
     HKALIKVLLL EAYASEYPHS HLLCDRLWQK TLEGDFSASN DAYYAIYEAI EIYLLKQNDT
     RRLEIVRRCF YLKCGVYLSR AKQGKDWRYP KMQQLVQDWQ WPESLINTLD DCEHWHSGQL
     NWFNEQLNEL LLASYQTLLR FASTHELNEG LRIEELGMLT RKLHTYFTQD EDQIAKLNLL
     WSSSVAESEV TMVSSSRESQ YYLYRQGPQP KNLLGESAIC KGKTPSALMI WACLNGVSTP
     DTKWYEFGQS KLKSKRLTDA AKRLLHFIDH DWRVSKRDLC QPWHFRKLIF VLNLDCDPTI
     NWRGQEMMVD FMNANVFSLG RKKENMLGAL DAICLNSWGE WQCHRFEGDT AVLQALAFVT
     PGLRRASLPV DMDVISCSQK LRPQLKLAVK NLLKQTARLC QQVQQSSILV QPLQISHIRY
     GIFFNPLGMA YEDLSDAKSF YQQLSRSHLV RLPRPALGDD PFSSMPNIIQ NFAAKGAIQY
     FLRQRGDNLD VFILDEENQL SHYVQHGSNM SELVNKVSHH YVFDEHYAAR ARFNIPQFFH
     LVRVAGDLTV APFGIDVTDQ DAEF
//