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A4Y8Y3

- GLSA_SHEPC

UniProt

A4Y8Y3 - GLSA_SHEPC

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Protein
Glutaminase
Gene
glsA, Sputcn32_2697
Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSPUT319224:GHAP-2780-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Sputcn32_2697
OrganismiShewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Taxonomic identifieri319224 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000006699: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotation
PRO_1000048359Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi319224.Sputcn32_2697.

Structurei

3D structure databases

ProteinModelPortaliA4Y8Y3.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A4Y8Y3-1 [UniParc]FASTAAdd to Basket

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MPELALLEEV VEKVRPLLGQ GKVANYIPAL ASVDAGKLGI AVTTVDGETL    50
GAGDYLEPFS IQSISKVFSL TLALTLYEEA EIWSRVGKEP SGHSFNSLVQ 100
VELERGKPRN PFINAGALVI ADLLQSRLGA PKHRMLELVR QLSQNDKVCF 150
DKQVADSEYQ HSARNAAIAY LMKSFGNFQG DVDTVLRTYF HYCALKMNCA 200
DLSRAMLYLA NRGKTVDGTE LISQVQTRQL NALLATSGLY DGAGEFAYRV 250
GMPGKSGVGG GIIAVIPGEL SICVWSPELD ENGNSLAGTA MLEHLSQRLG 300
RSIF 304
Length:304
Mass (Da):32,911
Last modified:May 29, 2007 - v1
Checksum:iD9C219EE77DEC89B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000681 Genomic DNA. Translation: ABP76416.1.
RefSeqiYP_001184215.1. NC_009438.1.

Genome annotation databases

EnsemblBacteriaiABP76416; ABP76416; Sputcn32_2697.
GeneIDi5079908.
KEGGispc:Sputcn32_2697.
PATRICi23554320. VBIShePut135485_2816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000681 Genomic DNA. Translation: ABP76416.1 .
RefSeqi YP_001184215.1. NC_009438.1.

3D structure databases

ProteinModelPortali A4Y8Y3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 319224.Sputcn32_2697.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP76416 ; ABP76416 ; Sputcn32_2697 .
GeneIDi 5079908.
KEGGi spc:Sputcn32_2697.
PATRICi 23554320. VBIShePut135485_2816.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SPUT319224:GHAP-2780-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CN-32 / ATCC BAA-453.

Entry informationi

Entry nameiGLSA_SHEPC
AccessioniPrimary (citable) accession number: A4Y8Y3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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