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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Sputcn32_2224
OrganismiShewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Taxonomic identifieri319224 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000006699 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000451161 – 236Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST236

Interactioni

Protein-protein interaction databases

STRINGi319224.Sputcn32_2224

Structurei

3D structure databases

ProteinModelPortaliA4Y7L2
SMRiA4Y7L2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A4Y7L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSLSFLNHE FEAFPSPELA LTDPNGLLAI GGDLRPERLL TAYYNGIFPW
60 70 80 90 100
FNADDPILWW SPDPRAIFML GKIRISTSLC KYLKKQPWHF TINHAFTSVM
110 120 130 140 150
AGCAEPRPKQ NGTWITDEIQ MAYRELHQNG HAHSIEVWEG EQLIGGLYGL
160 170 180 190 200
AIGQVFCGES MFHRQTNASK AAIVVLQQHL IKRGFKLIDA QVMNPHLESL
210 220 230
GAKAIKRTHF IELLTQFRDK KVHPDAWIPS EVFLEL
Length:236
Mass (Da):26,891
Last modified:May 29, 2007 - v1
Checksum:i591ED96438429F4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000681 Genomic DNA Translation: ABP75945.1
RefSeqiWP_011789117.1, NC_009438.1

Genome annotation databases

EnsemblBacteriaiABP75945; ABP75945; Sputcn32_2224
KEGGispc:Sputcn32_2224

Similar proteinsi

Entry informationi

Entry nameiLFTR_SHEPC
AccessioniPrimary (citable) accession number: A4Y7L2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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