A4Y7K5 (DCD_SHEPC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Sputcn32_2217

Organism

Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) [Complete proteome] [HAMAP]

Taxonomic identifier

319224 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella putrefaciens

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009811

Sequences

	Sequence		Length	Mass (Da)
	A4Y7K5 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 6BC2BB1F569060E6	FASTA	193	21,209
	10 20 30 40 50 60 MRLTDIEIEQ ALDNGTIVIE PRPSIDAISG VSVDVRLGGQ FRVFKDHTAP FIDLSGPSGE 70 80 90 100 110 120 MQAALDRVMS EIIEIPDGEA FFLHPGELAL AVTYESVTLP ADIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WQGKIVLEFY NSGKLPLALR PRMTIGALNF ERLSGPVARP YNTRKNAKYK 190 DQQEAVASRI SQD

References

[1]

"Complete sequence of Shewanella putrefaciens CN-32." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Fredrickson J., Tiedje J., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CN-32 / ATCC BAA-453.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000681 Genomic DNA. Translation: ABP75938.1.
RefSeq	YP_001183737.1. NC_009438.1.
3D structure databases
ProteinModelPortal	A4Y7K5.
SMR	A4Y7K5. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	319224.Sputcn32_2217.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABP75938; ABP75938; Sputcn32_2217.
GeneID	5080339.
KEGG	spc:Sputcn32_2217.
PATRIC	23553270. VBIShePut135485_2312.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	SPUT319224:GHAP-2278-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_SHEPC

Accession

Primary (citable) accession number: A4Y7K5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 29, 2007
Last modified:	May 29, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program