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Protein

Ubiquinone biosynthesis O-methyltransferase

Gene

ubiG

Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n.UniRule annotation
S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei39S-adenosyl-L-methionineUniRule annotation1
Binding sitei59S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei80S-adenosyl-L-methionineUniRule annotation1
Binding sitei124S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processUbiquinone biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00232

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinone biosynthesis O-methyltransferaseUniRule annotation
Alternative name(s):
2-polyprenyl-6-hydroxyphenol methylaseUniRule annotation (EC:2.1.1.222UniRule annotation)
3-demethylubiquinone 3-O-methyltransferaseUniRule annotation (EC:2.1.1.64UniRule annotation)
Gene namesi
Name:ubiGUniRule annotation
Ordered Locus Names:Sputcn32_2071
OrganismiShewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Taxonomic identifieri319224 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000006699 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000139231 – 236Ubiquinone biosynthesis O-methyltransferaseAdd BLAST236

Interactioni

Protein-protein interaction databases

STRINGi319224.Sputcn32_2071

Structurei

3D structure databases

ProteinModelPortaliA4Y759
SMRiA4Y759
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. UbiG/COQ3 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RFD Bacteria
COG2227 LUCA
HOGENOMiHOG000278065
KOiK00568
OMAiGTHDWEK
OrthoDBiPOG091H064Z

Family and domain databases

HAMAPiMF_00472 UbiG, 1 hit
InterProiView protein in InterPro
IPR029063 SAM-dependent_MTases
IPR010233 UbiG_MeTrfase
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR01983 UbiG, 1 hit

Sequencei

Sequence statusi: Complete.

A4Y759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQHNTNVDPQ EIAKFERMAE TWWDLNGEFK PLHLLNPLRL NYIDQTAGGI
60 70 80 90 100
FGKKVLDVGC GGGILSESMA RIGAEVDGLD MGEEPLEVAR LHALETGVNI
110 120 130 140 150
TYVKNTAEAH SQDHQGYYDV VTCMEMLEHV PNPQSVIKAC CDMVKPGGFV
160 170 180 190 200
FFSTINRNLR SYVETILGAE YLLKMLPVGT HDHNKFIKPS ELIELVDNTD
210 220 230
LICKDAVGIT YNPLTGIFKY TPRVDVNYMI ATQKVD
Length:236
Mass (Da):26,377
Last modified:May 29, 2007 - v1
Checksum:i7836B9C474A42683
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000681 Genomic DNA Translation: ABP75792.1
RefSeqiWP_011919356.1, NC_009438.1

Genome annotation databases

EnsemblBacteriaiABP75792; ABP75792; Sputcn32_2071
KEGGispc:Sputcn32_2071

Similar proteinsi

Entry informationi

Entry nameiUBIG_SHEPC
AccessioniPrimary (citable) accession number: A4Y759
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: April 25, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health