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Reviewed, UniProtKB/Swiss-Prot A4XWE6 (ASTB_PSEMY)

Last modified June 16, 2009. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    N-succinylarginine dihydrolase
    EC=3.5.3.23
Gene names
Name: astB
Ordered Locus Names: Pmen_2907
OrganismPseudomonas mendocina (strain ymp) [Complete proteome] [HAMAP]
Taxonomic identifier399739 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

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Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity.

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

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Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448N-succinylarginine dihydrolase HAMAP MF_01172
PRO_1000065732

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2501 By similarity
Active site3711Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2141Substrate By similarity
Binding site2521Substrate By similarity
Binding site3651Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
A4XWE6-1 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: FCF434B81E25F748

FASTA44848,693
        10         20         30         40         50         60 
MTAYEMNFDG LVGPTHNYGG LSYGNVASQS NSQAISNPKE AAKQGLAKMK ALMDMGFKQG 

        70         80         90        100        110        120 
VLAPQERPDV AALRRLGFTG SDPEVIARAA REAMPLLVAS CSASSMWTAN ACTVSPSADT 

       130        140        150        160        170        180 
ADARVHFTAA NLNCKFHRSI EHPTTSRVLQ AMFASQEHFA HHPALPAVSQ FGDEGAANHT 

       190        200        210        220        230        240 
RFCKSYGEPG VEFFVYGRSA FDSRYPAPAR YPARQTLEAS QAVARLHGLS EEGVVYAQQN 

       250        260        270        280        290        300 
PAVIDQGVFH NDVIAVGNGE VLFYHQDAFL DTDKVLGELG SKLAGRGGNF QAVCVPNSAV 

       310        320        330        340        350        360 
SVEDAVKSYL FNSQLLTRAD GSMLLVVPEE CRNNASVWRY LEQLTAGNGP IREVRVFDLK 

       370        380        390        400        410        420 
QSMQNGGGPA CLRLRVALKE QELAAVNPGV VMSLELHDRL VAWVDKHYRD RLSEADLADP 

       430        440 
QLLIECRTAL DELTQILKLG SVYPFQMT

« Hide

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References

[1]"Complete sequence of Pseudomonas mendocina ymp."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Hersman L., Dubois J., Maurice P., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000680 Genomic DNA. Translation: ABP85662.1.
RefSeqYP_001188394.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5107625.
GenomeReviewsGene locus Pmen_2907 in contig CP000680_GR.
KEGGpmy:Pmen_2907.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA4XWE6. HFAHHPA.

Family and domain databases

HAMAPMF_01172.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. arg_catab_astB. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameASTB_PSEMY
AccessionPrimary (citable) accession number: A4XWE6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: June 16, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents