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A4XUY7

- A4XUY7_PSEMY

UniProt

A4XUY7 - A4XUY7_PSEMY

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Pmen_2397

Organism
Pseudomonas mendocina (strain ymp)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei146 – 1461SubstrateUniRule annotation
    Sitei255 – 2551Critical for catalysisUniRule annotation
    Metal bindingi350 – 3501Magnesium or manganese
    Sitei420 – 4201Critical for catalysisUniRule annotation
    Binding sitei547 – 5471SubstrateUniRule annotation
    Metal bindingi548 – 5481Magnesium or manganese
    Metal bindingi552 – 5521Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciPMEN399739:GHR6-2441-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Pmen_2397Imported
    OrganismiPseudomonas mendocina (strain ymp)Imported
    Taxonomic identifieri399739 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000229: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi399739.Pmen_2397.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 1408Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiSIVKLMQ.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4XUY7-1 [UniParc]FASTAAdd to Basket

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    MSTPSKIIYT FTDEAPALAT YSLLPIVEAF AASADISVET RDISLAGRIL    50
    ASFADRLDAD KRIDDDLAKL AELTLQPDAN IIKLPNISAS VPQLKAAIAE 100
    LQAQGYNIPD FPEDPQSEED KEVRARYAKV LGSAVNPVLR EGNSDRRAPA 150
    AVKAYARKHP HSMGKWSMAS QSHADYMRGG DFFSSEQSIT MAKAGDVRIE 200
    FVGKDGKVEV KKQLALQEGE VFDSMFMSCR KLRDFFEKTL QDCKETGVMW 250
    SLHVKATMMK VSHPIVFGHA VSVYYKDVFD KYGELFKELG VNPNNGISSV 300
    YDKIKALPAS QQEEILHDIH EVYSHRPEMA MVDSVKGITN LHIPSDVIVD 350
    ASMPAMIRNS GQMWGKDGKQ KDTKAVMPES TYARIYQEMI NFCKTNGAFD 400
    PTTMGSVPNV GLMAQKAEEY GSHDKTFEMT ADGTMRVVAA DGTVLMQHQV 450
    EAGDIWRACQ TKDAPIRDWV KLAVTRARQS NTPAIFWLDP ERAHDRELQK 500
    KVELYLKDHD LTGLDIRMMG YNEAIRVSME RMIRGLDTIS VTGNVLRDYL 550
    TDLFPIMELG TSAKMLSIVP LMAGGGMYET GAGGSAPKHV QQLVEENYLR 600
    WDSLGEFLAL AVSLEETGIK TNNAKAKVLG KTLDQATGKL LDNNKSPARK 650
    VGEIDNRGSH FYLALYWAQA LAEQNDDAEL KAHFAPLAKQ LTEQEATIVG 700
    ELAAVQGKPV DIGGYYRSNP ELTSQVMRPS ATFNAALAAL NA 742
    Length:742
    Mass (Da):81,923
    Last modified:May 29, 2007 - v1
    Checksum:i0AF83F12B252FA9C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000680 Genomic DNA. Translation: ABP85153.1.
    RefSeqiYP_001187885.1. NC_009439.1.

    Genome annotation databases

    EnsemblBacteriaiABP85153; ABP85153; Pmen_2397.
    GeneIDi5108237.
    KEGGipmy:Pmen_2397.
    PATRICi19911329. VBIPseMen131592_2419.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000680 Genomic DNA. Translation: ABP85153.1 .
    RefSeqi YP_001187885.1. NC_009439.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399739.Pmen_2397.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP85153 ; ABP85153 ; Pmen_2397 .
    GeneIDi 5108237.
    KEGGi pmy:Pmen_2397.
    PATRICi 19911329. VBIPseMen131592_2419.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi SIVKLMQ.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci PMEN399739:GHR6-2441-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ympImported.

    Entry informationi

    Entry nameiA4XUY7_PSEMY
    AccessioniPrimary (citable) accession number: A4XUY7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 29, 2007
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3