SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A4XUY7

- A4XUY7_PSEMY

UniProt

A4XUY7 - A4XUY7_PSEMY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
Pmen_2397
Organism
Pseudomonas mendocina (strain ymp)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461Substrate By similarityUniRule annotation
Sitei255 – 2551Critical for catalysis By similarityUniRule annotation
Metal bindingi350 – 3501Magnesium or manganese By similarityUniRule annotation
Sitei420 – 4201Critical for catalysis By similarityUniRule annotation
Binding sitei547 – 5471Substrate By similarityUniRule annotation
Metal bindingi548 – 5481Magnesium or manganese By similarityUniRule annotation
Metal bindingi552 – 5521Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPMEN399739:GHR6-2441-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Pmen_2397Imported
OrganismiPseudomonas mendocina (strain ymp)Imported
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000229: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi399739.Pmen_2397.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate binding By similarityUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiSIVKLMQ.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

A4XUY7-1 [UniParc]FASTAAdd to Basket

« Hide

MSTPSKIIYT FTDEAPALAT YSLLPIVEAF AASADISVET RDISLAGRIL    50
ASFADRLDAD KRIDDDLAKL AELTLQPDAN IIKLPNISAS VPQLKAAIAE 100
LQAQGYNIPD FPEDPQSEED KEVRARYAKV LGSAVNPVLR EGNSDRRAPA 150
AVKAYARKHP HSMGKWSMAS QSHADYMRGG DFFSSEQSIT MAKAGDVRIE 200
FVGKDGKVEV KKQLALQEGE VFDSMFMSCR KLRDFFEKTL QDCKETGVMW 250
SLHVKATMMK VSHPIVFGHA VSVYYKDVFD KYGELFKELG VNPNNGISSV 300
YDKIKALPAS QQEEILHDIH EVYSHRPEMA MVDSVKGITN LHIPSDVIVD 350
ASMPAMIRNS GQMWGKDGKQ KDTKAVMPES TYARIYQEMI NFCKTNGAFD 400
PTTMGSVPNV GLMAQKAEEY GSHDKTFEMT ADGTMRVVAA DGTVLMQHQV 450
EAGDIWRACQ TKDAPIRDWV KLAVTRARQS NTPAIFWLDP ERAHDRELQK 500
KVELYLKDHD LTGLDIRMMG YNEAIRVSME RMIRGLDTIS VTGNVLRDYL 550
TDLFPIMELG TSAKMLSIVP LMAGGGMYET GAGGSAPKHV QQLVEENYLR 600
WDSLGEFLAL AVSLEETGIK TNNAKAKVLG KTLDQATGKL LDNNKSPARK 650
VGEIDNRGSH FYLALYWAQA LAEQNDDAEL KAHFAPLAKQ LTEQEATIVG 700
ELAAVQGKPV DIGGYYRSNP ELTSQVMRPS ATFNAALAAL NA 742
Length:742
Mass (Da):81,923
Last modified:May 29, 2007 - v1
Checksum:i0AF83F12B252FA9C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP85153.1.
RefSeqiYP_001187885.1. NC_009439.1.

Genome annotation databases

EnsemblBacteriaiABP85153; ABP85153; Pmen_2397.
GeneIDi5108237.
KEGGipmy:Pmen_2397.
PATRICi19911329. VBIPseMen131592_2419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP85153.1 .
RefSeqi YP_001187885.1. NC_009439.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 399739.Pmen_2397.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP85153 ; ABP85153 ; Pmen_2397 .
GeneIDi 5108237.
KEGGi pmy:Pmen_2397.
PATRICi 19911329. VBIPseMen131592_2419.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi SIVKLMQ.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PMEN399739:GHR6-2441-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ymp.

Entry informationi

Entry nameiA4XUY7_PSEMY
AccessioniPrimary (citable) accession number: A4XUY7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi