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A4XUY7

- A4XUY7_PSEMY

UniProt

A4XUY7 - A4XUY7_PSEMY

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Pmen_2397

Organism
Pseudomonas mendocina (strain ymp)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461SubstrateUniRule annotation
Sitei255 – 2551Critical for catalysisUniRule annotation
Sitei420 – 4201Critical for catalysisUniRule annotation
Binding sitei547 – 5471SubstrateUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPMEN399739:GHR6-2441-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Pmen_2397Imported
OrganismiPseudomonas mendocina (strain ymp)Imported
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000229: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi399739.Pmen_2397.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiSIVKLMQ.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

A4XUY7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTPSKIIYT FTDEAPALAT YSLLPIVEAF AASADISVET RDISLAGRIL
60 70 80 90 100
ASFADRLDAD KRIDDDLAKL AELTLQPDAN IIKLPNISAS VPQLKAAIAE
110 120 130 140 150
LQAQGYNIPD FPEDPQSEED KEVRARYAKV LGSAVNPVLR EGNSDRRAPA
160 170 180 190 200
AVKAYARKHP HSMGKWSMAS QSHADYMRGG DFFSSEQSIT MAKAGDVRIE
210 220 230 240 250
FVGKDGKVEV KKQLALQEGE VFDSMFMSCR KLRDFFEKTL QDCKETGVMW
260 270 280 290 300
SLHVKATMMK VSHPIVFGHA VSVYYKDVFD KYGELFKELG VNPNNGISSV
310 320 330 340 350
YDKIKALPAS QQEEILHDIH EVYSHRPEMA MVDSVKGITN LHIPSDVIVD
360 370 380 390 400
ASMPAMIRNS GQMWGKDGKQ KDTKAVMPES TYARIYQEMI NFCKTNGAFD
410 420 430 440 450
PTTMGSVPNV GLMAQKAEEY GSHDKTFEMT ADGTMRVVAA DGTVLMQHQV
460 470 480 490 500
EAGDIWRACQ TKDAPIRDWV KLAVTRARQS NTPAIFWLDP ERAHDRELQK
510 520 530 540 550
KVELYLKDHD LTGLDIRMMG YNEAIRVSME RMIRGLDTIS VTGNVLRDYL
560 570 580 590 600
TDLFPIMELG TSAKMLSIVP LMAGGGMYET GAGGSAPKHV QQLVEENYLR
610 620 630 640 650
WDSLGEFLAL AVSLEETGIK TNNAKAKVLG KTLDQATGKL LDNNKSPARK
660 670 680 690 700
VGEIDNRGSH FYLALYWAQA LAEQNDDAEL KAHFAPLAKQ LTEQEATIVG
710 720 730 740
ELAAVQGKPV DIGGYYRSNP ELTSQVMRPS ATFNAALAAL NA
Length:742
Mass (Da):81,923
Last modified:May 29, 2007 - v1
Checksum:i0AF83F12B252FA9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000680 Genomic DNA. Translation: ABP85153.1.
RefSeqiYP_001187885.1. NC_009439.1.

Genome annotation databases

EnsemblBacteriaiABP85153; ABP85153; Pmen_2397.
GeneIDi5108237.
KEGGipmy:Pmen_2397.
PATRICi19911329. VBIPseMen131592_2419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000680 Genomic DNA. Translation: ABP85153.1 .
RefSeqi YP_001187885.1. NC_009439.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 399739.Pmen_2397.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP85153 ; ABP85153 ; Pmen_2397 .
GeneIDi 5108237.
KEGGi pmy:Pmen_2397.
PATRICi 19911329. VBIPseMen131592_2419.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi SIVKLMQ.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PMEN399739:GHR6-2441-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ympImported.

Entry informationi

Entry nameiA4XUY7_PSEMY
AccessioniPrimary (citable) accession number: A4XUY7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: November 26, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3