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Protein

Transaldolase

Gene

tal

Organism
Pseudomonas mendocina (strain ymp)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei125Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciPMEN399739:G1G8Q-1970-MONOMER.
UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:Pmen_1931
OrganismiPseudomonas mendocina (strain ymp)
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000229 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000145141 – 308TransaldolaseAdd BLAST308

Proteomic databases

PRIDEiA4XTM7.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi399739.Pmen_1931.

Structurei

3D structure databases

ProteinModelPortaliA4XTM7.
SMRiA4XTM7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3. Bacteria.
COG0176. LUCA.
HOGENOMiHOG000281234.
KOiK00616.
OMAiMAFDKLH.
OrthoDBiPOG091H05RO.

Family and domain databases

CDDicd00957. Transaldolase_TalAB. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00492. Transaldolase_1. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR004730. Transaldolase_1.
IPR018225. Transaldolase_AS.
PANTHERiPTHR10683. PTHR10683. 1 hit.
PTHR10683:SF20. PTHR10683:SF20. 1 hit.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00874. talAB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A4XTM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSKLEQLKQ FTTVVADTGD LDAIARLKPV DATTNPSLLL KAASLPGYAD
60 70 80 90 100
LLKQAVSTGK GDPGLACDHF AVAVGQEILK VIPGRISTEV DARLSFDTGA
110 120 130 140 150
TLLRAERLIG LYEQAGIGRE RVLIKIASTW EGIRAAEQLE KSGVQTNLTL
160 170 180 190 200
LFSFAQAQAC ADAGVFLISP FVGRIYDWYK KTEGRDFVGS EDPGVQSVSR
210 220 230 240 250
IYDYYKANGY DTVVMGASFR NLGQIEALAG CDRLTISPEL LQKLAEDEGE
260 270 280 290 300
LSRKLAPGGA GEARQTLDES AFRWALNEDA MATEKLAEGI RLFARDQEKL

EALLAAKA
Length:308
Mass (Da):33,279
Last modified:May 29, 2007 - v1
Checksum:iB115962159D147A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000680 Genomic DNA. Translation: ABP84693.1.
RefSeqiWP_012018392.1. NC_009439.1.

Genome annotation databases

EnsemblBacteriaiABP84693; ABP84693; Pmen_1931.
GeneIDi5110059.
KEGGipmy:Pmen_1931.
PATRICifig|399739.8.peg.1955.

Similar proteinsi

Entry informationi

Entry nameiTAL_PSEMY
AccessioniPrimary (citable) accession number: A4XTM7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome