A4XQN7 (A4XQN7_PSEMY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 1 HAMAP MF_01023

Gene names

Name:	hisC1 HAMAP MF_01023
Ordered Locus Names:	Pmen_0885

Organism

Pseudomonas mendocina (strain ymp) [Complete proteome] [HAMAP] EMBL ABP83653.1

Taxonomic identifier

399739 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ABP83653.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	210	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	A4XQN7 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 3CEA3ECC2637276E	FASTA	350	38,359
	10 20 30 40 50 60 MSKFWSPFVK DLVPYVPGEQ PKLSKLVKLN TNENPYGPSP KAIAAMQAEL NDDLRLYPDP 70 80 90 100 110 120 NGDRLKQAVA DYYGVSTAQV FVGNGSDEVL AHAFHGLFQH DKPLLFPDVT YSFYPVYCGL 130 140 150 160 170 180 YGIEFEALAL DENFQIRVED YARPNAGIIF PNPNAPTGCL LPLETVERLL QGSPDSVVLV 190 200 210 220 230 240 DEAYIDFGGD TAISLVDKYP NLLVTQTLSK SRSLAGLRVG IAVGHPDLIE ALERIKNSFN 250 260 270 280 290 300 SYPLDRMAIA GAAAAFADRE YFERTCRQVI ASREAVVAGL QGLGFEVLPS AANFVFARHS 310 320 330 340 350 DKDAATLAAG LREQGVIVRH FKQPRIAQFL RITIGTPEQN QALLDALQGL

References

[1]

"Complete sequence of Pseudomonas mendocina ymp." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Hersman L., Dubois J., Maurice P., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ymp.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000680 Genomic DNA. Translation: ABP83653.1.
RefSeq	YP_001186385.1. NC_009439.1.
3D structure databases
ProteinModelPortal	A4XQN7.
ModBase	Search...
Protein-protein interaction databases
STRING	A4XQN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5108743.
GenomeReviews	Gene locus Pmen_0885 in contig CP000680_GR.
KEGG	pmy:Pmen_0885.
PATRIC	19908202. VBIPseMen131592_0894.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
HOGENOM	HBG646350.
OMA	MKNSFNS.
ProtClustDB	PRK05387.
Enzyme and pathway databases
BioCyc	PMEN399739:PMEN_0885-MONOMER.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4XQN7_PSEMY

Accession

Primary (citable) accession number: A4XQN7

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)