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A4XPN9

- SYR_PSEMY

UniProt

A4XPN9 - SYR_PSEMY

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas mendocina (strain ymp)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMEN399739:GHR6-535-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Pmen_0535
OrganismiPseudomonas mendocina (strain ymp)
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000229: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 579579Arginine--tRNA ligasePRO_1000018093Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi399739.Pmen_0535.

Structurei

3D structure databases

ProteinModelPortaliA4XPN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi127 – 13711"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247212.
KOiK01887.
OMAiMEHMGFG.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4XPN9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKDSIRHLIQ QALDRLTADG VLPAGLTPAI QVENTKDKSH GDFASNIAMM
60 70 80 90 100
LAKPAGMKPR DLAEKLIAAL PADAGIAKVE IAGPGFLNFF QNSDALAQRL
110 120 130 140 150
EAALADAQLG VHKNGPAQRV VVDLSAPNLA KEMHVGHLRS TIIGDGVARV
160 170 180 190 200
LEFLGDTVIR QNHVGDWGTQ FGMLLAYMQE NPAAAESELA DLEGFYRAAK
210 220 230 240 250
KRFDESPEFA DRARELVVQL QAGDAECLRL WHRFNDISLS HCQALYDRLG
260 270 280 290 300
VKLSMADVKG ESAYNDDLPQ VVADLAAKGL LTEDNGAQCV FMDEFKNAEG
310 320 330 340 350
NPLPLIVQKA GGGYLYATTD LAATRYRAGV LKADRVLYFV DQRQALHFQM
360 370 380 390 400
VFACARLAGF VPASMELEHM GFGTMNGPDG RPFKTRDGGT VKLVQLLDEA
410 420 430 440 450
EQRAYELVKS KNPELAEDEL RRIARVVGIA SVKYADLSKH RASDYSFNFD
460 470 480 490 500
LMLSFEGNTA PYLLYAYTRV AGVFRKLGKG IDEIGGRIAL VAEQEQALAA
510 520 530 540 550
KLAQFGELLA SVADKGTPHM LCSYLYDLAG LFSSFYENCP ILAAEDEATR
560 570
DSRLRLTALT GRTLKQGLEL LGLETLERM
Length:579
Mass (Da):63,275
Last modified:May 29, 2007 - v1
Checksum:iE8DAC4CBB19C3012
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP83305.1.
RefSeqiYP_001186037.1. NC_009439.1.

Genome annotation databases

EnsemblBacteriaiABP83305; ABP83305; Pmen_0535.
GeneIDi5108159.
KEGGipmy:Pmen_0535.
PATRICi19907489. VBIPseMen131592_0543.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP83305.1 .
RefSeqi YP_001186037.1. NC_009439.1.

3D structure databases

ProteinModelPortali A4XPN9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 399739.Pmen_0535.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP83305 ; ABP83305 ; Pmen_0535 .
GeneIDi 5108159.
KEGGi pmy:Pmen_0535.
PATRICi 19907489. VBIPseMen131592_0543.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247212.
KOi K01887.
OMAi MEHMGFG.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci PMEN399739:GHR6-535-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ymp.

Entry informationi

Entry nameiSYR_PSEMY
AccessioniPrimary (citable) accession number: A4XPN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3