ID   BETB_PSEMY              Reviewed;         490 AA.
AC   A4XPI6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   16-JUN-2009, entry version 14.
DE   RecName: Full=Betaine aldehyde dehydrogenase;
DE            Short=BADH;
DE            EC=1.2.1.8;
GN   Name=betB; OrderedLocusNames=Pmen_0482;
OS   Pseudomonas mendocina (strain ymp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=399739;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C.,
RA   Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Hersman L., Dubois J., Maurice P.,
RA   Richardson P.;
RT   "Complete sequence of Pseudomonas mendocina ymp.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine +
CC       NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis
CC       via choline pathway; betaine from betaine aldehyde: step 1/1.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; CP000680; ABP83252.1; -; Genomic_DNA.
DR   RefSeq; YP_001185984.1; -.
DR   GeneID; 5108401; -.
DR   GenomeReviews; CP000680_GR; Pmen_0482.
DR   KEGG; pmy:Pmen_0482; -.
DR   OMA; A4XPI6; TLKEVTM.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from c...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00804; -; 1.
DR   InterPro; IPR016160; Ald_DH_CS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH.
DR   InterPro; IPR011264; Betaine_Ald_DH.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   TIGRFAMs; TIGR01804; BADH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    490       Betaine aldehyde dehydrogenase.
FT                                /FTId=PRO_1000047048.
FT   NP_BIND     229    234       NAD (By similarity).
FT   ACT_SITE    252    252       By similarity.
FT   ACT_SITE    286    286       By similarity.
SQ   SEQUENCE   490 AA;  53122 MW;  D0DE6E4DE8909B18 CRC64;
     MPRFAEQQLY IGGQYVAASS GQTFDSINPA TGEVLAKVQR ASQADVDRAV ASAAEGQKVW
     AAMTAMQRSR ILRRAVDILR ERNDELAELE TLDTGKPLSE TRYVDIVTGA DVLEYYAGLI
     PAIEGEQIPL RESSFVYTRR EPLGVVAGIG AWNYPIQIAL WKSAPALAAG NAMIFKPSEV
     TSLTALKLAE IYTEAGLPAG VFNVLTGSGR EVGQWLTEHP GIEKVSFTGG TVTGKKVMAS
     ASSSSLKEVT MELGGKSPLI VFEDADLDRA ADIAVMANFY SSGQVCTNGT RVFVPRMLQA
     RFEAKVLERV KRIRLGDPLD DATNFGPLVS YAHMESVLGY IEKGRSEGAR LLIGGTRVSD
     GDYAKGAYVA PTVFTDCRDD MTIVREEIFG PVMSILIYDS EEEVIRRAND TDYGLAAGVV
     TRDLNRAHRV IHKLEAGICW INTWGESPAE MPVGGYKQSG VGRENGLVTL GHYTRIKSVQ
     VELGGYSSVF
//