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A4XP61 (ARGA_PSEMY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Amino-acid acetyltransferase
EC=2.3.1.1
Alternative name(s):
N-acetylglutamate synthase
Short name=AGS
Short name=NAGS
Gene names
Name:argA
Ordered Locus Names:Pmen_0354
OrganismPseudomonas mendocina (strain ymp) [Complete proteome] [HAMAP]
Taxonomic identifier399739 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01105

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01105

Subcellular location

Cytoplasm By similarity HAMAP MF_01105.

Sequence similarities

Belongs to the acetyltransferase family. ArgA subfamily.

Contains 1 N-acetyltransferase domain.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacetyl-CoA:L-glutamate N-acetyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 432432Amino-acid acetyltransferase HAMAP MF_01105
PRO_1000084818

Regions

Domain286 – 425140N-acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
A4XP61 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 24CB49A0AAA9381D

FASTA43247,732
        10         20         30         40         50         60 
MHDYVTWLRH ASPYINAHRD RTFVVMLPGE GIAHPNFANI VHDLVLLHSL GVRLVLVHGS 

        70         80         90        100        110        120 
RPQIEARLAA RGLTPHFHRD LRITDAPTLE CVIDAVGQLR IAIEARLSMD MAASPMQGSR 

       130        140        150        160        170        180 
LRLTSGNFVT ARPIGVLDGV DYHHTGEVRR IDRKGINRQL DERSIVLLSP LGYSPTGEIF 

       190        200        210        220        230        240 
NLACEDVATR AAIDLGADKL LLFGAEDGLL DEHGQLVREL RPQQVPAHLA RLGSNYQGEL 

       250        260        270        280        290        300 
LDAAAQACRG GVGRSHIVSY ATDGALLSEL FTRTGNGTLV AQEQFESLRE ATIEDVGGLI 

       310        320        330        340        350        360 
ELISPLEEQG ILVRRSREVL EREIEQFSIV EREGLIIACA ALYPIADSDC GELACLAVNP 

       370        380        390        400        410        420 
DYRHGGRGDE LLARIEARAR AQGLKTLFVL TTRTAHWFRE RGFEPSSVER MPAARASLYN 

       430 
YQRNSKVFEK AL

« Hide

References

[1]"Complete sequence of Pseudomonas mendocina ymp."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Hersman L., Dubois J., Maurice P., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ymp.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000680 Genomic DNA. Translation: ABP83127.1.
RefSeqYP_001185859.1. NC_009439.1.

3D structure databases

ProteinModelPortalA4XP61.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4XP61.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5108276.
GenomeReviewsGene locus Pmen_0354 in contig CP000680_GR.
KEGGpmy:Pmen_0354.
PATRIC19907128. VBIPseMen131592_0363.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0548.
HOGENOMHBG545264.
OMAAFNLAME.
PhylomeDBA4XP61.
ProtClustDBPRK05279.

Enzyme and pathway databases

BioCycPMEN399739:PMEN_0354-MONOMER.

Family and domain databases

HAMAPMF_01105. N-acetyl_glu_synth.
[Tree]
InterProIPR000182. AcTrfase_GCN5-related_dom.
IPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR010167. NH2A_AcTrfase_ArgA.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KOK14682.
PfamPF00696. AA_kinase. 1 hit.
PF00583. Acetyltransf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000423. ArgA. 1 hit.
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMsTIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARGA_PSEMY
AccessionPrimary (citable) accession number: A4XP61
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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