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A4XNJ7

- GLSA_PSEMY

UniProt

A4XNJ7 - GLSA_PSEMY

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Protein
Glutaminase
Gene
glsA, Pmen_0139
Organism
Pseudomonas mendocina (strain ymp)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611Substrate By similarity
Binding sitei111 – 1111Substrate By similarity
Binding sitei155 – 1551Substrate By similarity
Binding sitei162 – 1621Substrate By similarity
Binding sitei186 – 1861Substrate By similarity
Binding sitei238 – 2381Substrate By similarity
Binding sitei256 – 2561Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPMEN399739:GHR6-138-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Pmen_0139
OrganismiPseudomonas mendocina (strain ymp)
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000229: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302GlutaminaseUniRule annotation
PRO_1000048343Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi399739.Pmen_0139.

Structurei

3D structure databases

ProteinModelPortaliA4XNJ7.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A4XNJ7-1 [UniParc]FASTAAdd to Basket

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MQALLTEILD EVRPLIGQGK VADYIPALAG VVPDQLGIAV YGNDGQLHVA    50
GDARTPFSIQ SISKVFSLVQ AIGHSGEAIW QRLGHEPSGQ PFNSLVQLEF 100
ERGKPRNPFI NAGALVICDI NQSRYAAPAL SMRDFVRRLS GNPEVTVDNH 150
VAESEYQHRA RNAAAAYLMQ SFGNFHNEVE AVLRSYFSCC ALRMSCVDLA 200
RAFGFLANQG FCQHSGEQIL SPRQSKQINA IMATSGLYDE AGNFAYRVGL 250
PGKSGVGGGI VAVVPGQFSV CVWSPELNAA GNSLTGIKAL ELLSERIGWS 300
VF 302
Length:302
Mass (Da):32,540
Last modified:May 29, 2007 - v1
Checksum:i0955A297A14B51FD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP82913.1.
RefSeqiWP_011920466.1. NC_009439.1.
YP_001185645.1. NC_009439.1.

Genome annotation databases

EnsemblBacteriaiABP82913; ABP82913; Pmen_0139.
GeneIDi5106819.
KEGGipmy:Pmen_0139.
PATRICi19906679. VBIPseMen131592_0140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000680 Genomic DNA. Translation: ABP82913.1 .
RefSeqi WP_011920466.1. NC_009439.1.
YP_001185645.1. NC_009439.1.

3D structure databases

ProteinModelPortali A4XNJ7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 399739.Pmen_0139.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP82913 ; ABP82913 ; Pmen_0139 .
GeneIDi 5106819.
KEGGi pmy:Pmen_0139.
PATRICi 19906679. VBIPseMen131592_0140.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci PMEN399739:GHR6-138-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ymp.

Entry informationi

Entry nameiGLSA_PSEMY
AccessioniPrimary (citable) accession number: A4XNJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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