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A4XNJ7

- GLSA_PSEMY

UniProt

A4XNJ7 - GLSA_PSEMY

Protein

Glutaminase

Gene

glsA

Organism
Pseudomonas mendocina (strain ymp)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei61 – 611SubstrateUniRule annotation
    Binding sitei111 – 1111SubstrateUniRule annotation
    Binding sitei155 – 1551SubstrateUniRule annotation
    Binding sitei162 – 1621SubstrateUniRule annotation
    Binding sitei186 – 1861SubstrateUniRule annotation
    Binding sitei238 – 2381SubstrateUniRule annotation
    Binding sitei256 – 2561Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPMEN399739:GHR6-138-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:Pmen_0139
    OrganismiPseudomonas mendocina (strain ymp)
    Taxonomic identifieri399739 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000229: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 302302GlutaminasePRO_1000048343Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi399739.Pmen_0139.

    Structurei

    3D structure databases

    ProteinModelPortaliA4XNJ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiMSIAVWS.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4XNJ7-1 [UniParc]FASTAAdd to Basket

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    MQALLTEILD EVRPLIGQGK VADYIPALAG VVPDQLGIAV YGNDGQLHVA    50
    GDARTPFSIQ SISKVFSLVQ AIGHSGEAIW QRLGHEPSGQ PFNSLVQLEF 100
    ERGKPRNPFI NAGALVICDI NQSRYAAPAL SMRDFVRRLS GNPEVTVDNH 150
    VAESEYQHRA RNAAAAYLMQ SFGNFHNEVE AVLRSYFSCC ALRMSCVDLA 200
    RAFGFLANQG FCQHSGEQIL SPRQSKQINA IMATSGLYDE AGNFAYRVGL 250
    PGKSGVGGGI VAVVPGQFSV CVWSPELNAA GNSLTGIKAL ELLSERIGWS 300
    VF 302
    Length:302
    Mass (Da):32,540
    Last modified:May 29, 2007 - v1
    Checksum:i0955A297A14B51FD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000680 Genomic DNA. Translation: ABP82913.1.
    RefSeqiWP_011920466.1. NC_009439.1.
    YP_001185645.1. NC_009439.1.

    Genome annotation databases

    EnsemblBacteriaiABP82913; ABP82913; Pmen_0139.
    GeneIDi5106819.
    KEGGipmy:Pmen_0139.
    PATRICi19906679. VBIPseMen131592_0140.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000680 Genomic DNA. Translation: ABP82913.1 .
    RefSeqi WP_011920466.1. NC_009439.1.
    YP_001185645.1. NC_009439.1.

    3D structure databases

    ProteinModelPortali A4XNJ7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399739.Pmen_0139.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP82913 ; ABP82913 ; Pmen_0139 .
    GeneIDi 5106819.
    KEGGi pmy:Pmen_0139.
    PATRICi 19906679. VBIPseMen131592_0140.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi MSIAVWS.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci PMEN399739:GHR6-138-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ymp.

    Entry informationi

    Entry nameiGLSA_PSEMY
    AccessioniPrimary (citable) accession number: A4XNJ7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3