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A4XJW5 (A4XJW5_CALS8) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP MF_00104

EC=3.1.26.3 HAMAP MF_00104
Alternative name(s):
Ribonuclease III HAMAP MF_00104
Gene names
Name:rnc HAMAP MF_00104
Ordered Locus Names:Csac_1608
OrganismCaldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) [Complete proteome] [HAMAP]
Taxonomic identifier351627 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisCaldicellulosiruptor

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104 SAAS SAAS011907

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104 SAAS SAAS011907

Subcellular location

Cytoplasm By similarity HAMAP MF_00104 SAAS SAAS011907.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP MF_00104 SAAS SAAS011907

Contains 1 RNase III domain. HAMAP MF_00104 SAAS SAAS011907

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain1 – 126126RNase III By similarity HAMAP MF_00104
Domain153 – 22169DRBM By similarity HAMAP MF_00104

Sequences

Sequence LengthMass (Da)Tools
A4XJW5 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 57E17098A51FA103

FASTA22425,762
        10         20         30         40         50         60 
MTDIEKKLGY RFKNPNLLKL ALTHKSATHD DKSCYERLEF LGDAVLELVV SKYLFEHFPQ 

        70         80         90        100        110        120 
LSEGELTNLR ATIVCSETLS KVAETLNLKR YIVFGKNEKK EGFEGNKSIW SDVLEAIFGG 

       130        140        150        160        170        180 
IFLESGFDMA EKIVINLLEP FIKKAAEGKL FYDYKTKLQE FIQREKNVKI KYIDYENFED 

       190        200        210        220 
NLSRFKSELY IGKNKISEGY GNSKKEAQQE AALNALKKLG VIED 

« Hide

References

[1]"Genome sequence of the thermophilic hydrogen-producing bacterium Caldicellulosiruptor saccharolyticus DSM 8903."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A., VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J., Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M., Kengen S.M.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43494 / DSM 8903.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000679 Genomic DNA. Translation: ABP67200.1.
RefSeqYP_001180391.1. NC_009437.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA4XJW5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5087309.
GenomeReviewsGene locus Csac_1608 in contig CP000679_GR.
KEGGcsc:Csac_1608.
PATRIC21252924. VBICalSac56748_1771.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHBG744556.
OMASAYANLF.
ProtClustDBCLSK2473164.

Family and domain databases

HAMAPMF_00104. RNase_III.
[Tree]
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like.
IPR000999. RNase_III.
IPR011907. RNase_III_bac.
[Graphical view]
Gene3DG3DSA:3.30.160.20. dsRNA-bd-like. 1 hit.
G3DSA:1.10.1520.10. RNase_III. 1 hit.
KOK03685.
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4XJW5_CALS8
AccessionPrimary (citable) accession number: A4XJW5
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)