A4XIC0 (A4XIC0_CALS8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

Csac_1041

Organism

Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) [Complete proteome] [HAMAP] EMBL ABP66655.1

Taxonomic identifier

351627 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Caldicellulosiruptor › Caldocellum saccharolyticum

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL ABP66655.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4XIC0 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 95A6A3F9583FF17B	FASTA	387	43,698
	10 20 30 40 50 60 MSLYSRVWAE INLDNLIYNV NNIKEKILPN TQIMAVVKAD AYGHGAIEVS RVLVRNGINM 70 80 90 100 110 120 LAVAIIDEAL QLRHYNFDIP ILILGFTPFE LSEQVVENDI SQTVYTFEQA YYLNEAAKKI 130 140 150 160 170 180 GKKAKVHIKV DTGMGRIGFL CTKESIETII RIASLSHIEL EGIFSHFSSA DDPQSDNFTY 190 200 210 220 230 240 EQFLRFENFV KELNKNGVYF KYRHIANSAA AIRFPQYQLD IVRLGLVLYG LYPSEAVKTE 250 260 270 280 290 300 ISLKPVMSVK AKVINVKEVP EGYPISYNRK YVTPCKSKIA TIPIGYADGF TRVGSEKRYV 310 320 330 340 350 360 LINGEYAKVV GNVCMDQCMV DVTHIRDVKI GDEVVIIGKQ GKNEITADDL ASQIGTINYE 370 380 VICSVSKRIP RVYIRDGRVV KILNYIL

References

[1]

"Genome sequence of the thermophilic hydrogen-producing bacterium Caldicellulosiruptor saccharolyticus DSM 8903." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A., VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J., Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M., Kengen S.M.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43494 / DSM 8903.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000679 Genomic DNA. Translation: ABP66655.1.
RefSeq	YP_001179846.1. NC_009437.1.
3D structure databases
ProteinModelPortal	A4XIC0.
ModBase	Search...
Protein-protein interaction databases
STRING	351627.Csac_1041.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABP66655; ABP66655; Csac_1041.
GeneID	5089080.
KEGG	csc:Csac_1041.
PATRIC	21251718. VBICalSac56748_1174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0787.
HOGENOM	HOG000031444.
KO	K01775.
OMA	AAEKQHT.
ProtClustDB	CLSK2472912.
Enzyme and pathway databases
BioCyc	CSAC351627:GJ17-1070-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4XIC0_CALS8

Accession

Primary (citable) accession number: A4XIC0

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)