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A4XHL5 (GLGA_CALS8) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:Csac_0781
OrganismCaldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) [Complete proteome] [HAMAP]
Taxonomic identifier351627 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisCaldicellulosiruptor

Protein attributes

Sequence length477 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 477477Glycogen synthase HAMAP-Rule MF_00484
PRO_1000014344

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
A4XHL5 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 2AF09548267E7A31

FASTA47754,558
        10         20         30         40         50         60 
MNVLFAVSEA FPFAKTGGLA DVAYSLPKAL RKLGVDIRVI MPKYGDIPSD YTTKMKHLCH 

        70         80         90        100        110        120 
FTVPVGWRNQ YCGIEYLNFE GVPFYFIDNE YYFKRPGYYG YYDDGERFSY FSRAVCEAIY 

       130        140        150        160        170        180 
HLDFDVDIIH VNDWHTSVIP VLLKAHYSHS PKHQKIKTVL TIHNLRYQGV FPKEVMYDLL 

       190        200        210        220        230        240 
SLPDEYFDEN KLKFYDAISF LKGGIIFADK VVTVSKTYAN EIRTLSHGEG LHGLLSGIGE 

       250        260        270        280        290        300 
KLVGIVNGID YEVCNPATDK LIFVNYDANT FESRKKENKF RLQQMLNLPV SDDIVLIGMV 

       310        320        330        340        350        360 
SRLTKEKGID LIERILSRLL TLPVQLVILG AGDYHYEQMF KYYAIAYPSK VSANICYSEE 

       370        380        390        400        410        420 
LARKIYAGSD IYLMPSLTEP CGISQLIAMR YGTVPIVRET GGLKDTVKPY NQFTGEGWGF 

       430        440        450        460        470 
SFANYDPAEL FAIIKYALSI YSDKAQWRSI VHQAMTRDNS WNASAGEYNR VYEQLLK 

« Hide

References

[1]"Genome sequence of the thermophilic hydrogen-producing bacterium Caldicellulosiruptor saccharolyticus DSM 8903."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A., VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J., Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M., Kengen S.M.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43494 / DSM 8903.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000679 Genomic DNA. Translation: ABP66400.1.
RefSeqYP_001179591.1. NC_009437.1.

3D structure databases

ProteinModelPortalA4XHL5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING351627.Csac_0781.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP66400; ABP66400; Csac_0781.
GeneID5087654.
KEGGcsc:Csac_0781.
PATRIC21251134. VBICalSac56748_0889.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAVHCNDWQ.
OrthoDBEOG6JTC6Z.
ProtClustDBPRK00654.

Enzyme and pathway databases

BioCycCSAC351627:GJ17-802-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_CALS8
AccessionPrimary (citable) accession number: A4XHL5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways