A4XGG8 (A4XGG8_CALS8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycoside hydrolase family 2, TIM barrel EMBL ABP66003.1

Gene names

Ordered Locus Names:

Csac_0362

Organism

Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) [Complete proteome] [HAMAP]

Taxonomic identifier

351627 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Caldicellulosiruptor

Protein attributes

Sequence length	1026 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. SAAS SAAS023230

Ontologies

Keywords
Molecular function	Glycosidase SAAS SAAS023230 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular function	beta-galactosidase activity Inferred from electronic annotation. Source: InterPro carbohydrate binding Inferred from electronic annotation. Source: InterPro cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4XGG8 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 7E09068443BA2A80	FASTA	1,026	118,856
	10 20 30 40 50 60 MLDKNYYQNP KIQHINREEP RSSFIPFDNH QKALENEWEL SNLFRLLNGK WYFKLFEKPC 70 80 90 100 110 120 MVTEDIILAD TKSCNFDQII VPSNFQMFGY DIPIYTNTRY PIPVDPPFVP DINPTGVYKR 130 140 150 160 170 180 EFYISQEDLD KEIFVVFEGV DSAFYVYING KFAGFSKVSH MMHEFDITRF VQEGRNTITA 190 200 210 220 230 240 IVLKYSDGTY LEDQDKWRMS GIFRDVYLLL RPKVFVRDVY LKSTLSDDLK EGHLTAEIEI 250 260 270 280 290 300 KNRSNDQKEF SVEVQVFFDK TLIKSSNKSL RLSASGKQEI TFEFQIENPR LWSAELPNLY 310 320 330 340 350 360 TLIVALKDSS GGMLEIIPQN FGFRKIEIKD GVFYLNNVPI KLKGVNRHDM HPRVGFAVTR 370 380 390 400 410 420 KMMQEDITLM KQHNINCVRT SHYPNHPYFL ELCDRFGIYV IDEADLETHG FGAVGDWGLL 430 440 450 460 470 480 AKDPVWEDAF VERAKMMVKR DKNHPSIIMW SLGNESGYGP NHDKMAQWIR SYDNSRPIHY 490 500 510 520 530 540 ESARDAEVVD IVSVMYPSVE KFEEEGKKQE KRPFFMCEYA HAMGNGPGNL KEYWDVIYKY 550 560 570 580 590 600 PRLLGGCVWE WADHGILTKI PDGKEYYAYG GDFGDEPNDG NFCIDGLLFP DRTPSPGMIE 610 620 630 640 650 660 LKKVYEPVVI ELLDKESGIF KITNRYDFIS LNHIEVEWKL LSGGRVVKEG FVDVSDVLPR 670 680 690 700 710 720 SSKEVKIDEV KEVLESCKEE LFITFTAKLK NSLPWAKRGF VITKSQIALI EDTPQDAVQK 730 740 750 760 770 780 IEKVNVIFSK QNRFEVVNSP DKVEVFAGST LVEFCRWSGD LISLKHNGLD FIKSSPRFNL 790 800 810 820 830 840 WRAPTDNDVH IKNEWIKAGF DKLQRRIVNV SFEEHSEYFK VQTTSVYGAY SVKPVFEVTT 850 860 870 880 890 900 SYKVFKSGIV ETNVYAQALR QLPPLPKIGL QFMMPKEFEY VKYYGRGPHE NYPDIKQSAT 910 920 930 940 950 960 VEIYDMAIKD MYVPYIMPQE YGNRCDVRWA FVYNIYGIGL CIKGIPTFNF SAREYTDDVL 970 980 990 1000 1010 1020 TRAKHTYELT KADGIVVNVD YKIGGIGSQS CGPGPLEKYL IKDEKFEFCF YMIPVDSNSL DVEKLW

References

[1]

"Genome sequence of the thermophilic hydrogen-producing bacterium Caldicellulosiruptor saccharolyticus DSM 8903." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A., VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J., Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M., Kengen S.M.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43494 / DSM 8903.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000679 Genomic DNA. Translation: ABP66003.1.
RefSeq	YP_001179194.1. NC_009437.1.
3D structure databases
ProteinModelPortal	A4XGG8.
ModBase	Search...
Protein-protein interaction databases
STRING	A4XGG8.
Protein family/group databases
CAZy	GH2. Glycoside Hydrolase Family 2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5089009.
GenomeReviews	Gene locus Csac_0362 in contig CP000679_GR.
KEGG	csc:Csac_0362.
PATRIC	21250173. VBICalSac56748_0419.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3250.
HOGENOM	HBG670643.
OMA	PMNRWEN.
ProtClustDB	CLSK854227.
Family and domain databases
InterPro	IPR004199. B-gal_small/dom_5. IPR008979. Galactose-bd-like. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR006101. Glyco_hydro_2. IPR013812. Glyco_hydro_2/20_Ig-like. IPR023232. Glyco_hydro_2_AS. IPR023230. Glyco_hydro_2_CS. IPR006102. Glyco_hydro_2_Ig-like. IPR006104. Glyco_hydro_2_N. IPR006103. Glyco_hydro_2_TIM. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:2.60.40.320. Glyco_hydro_2/20_Ig-like. 2 hits. G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K01190.
Pfam	PF02929. Bgal_small_N. 1 hit. PF00703. Glyco_hydro_2. 1 hit. PF02836. Glyco_hydro_2_C. 1 hit. PF02837. Glyco_hydro_2_N. 1 hit. [Graphical view]
PRINTS	PR00132. GLHYDRLASE2.
SMART	SM01038. Bgal_small_N. 1 hit. [Graphical view]
SUPFAM	SSF49785. Gal_bind_like. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF49303. Glyco_hydro_2Ig. 2 hits. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit. PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4XGG8_CALS8

Accession

Primary (citable) accession number: A4XGG8

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)