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A4XFZ6 (COMB_CALS8) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71
Gene names
Name:comB
Ordered Locus Names:Csac_0183
OrganismCaldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) [Complete proteome] [HAMAP]
Taxonomic identifier351627 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Caldicellulosiruptor

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490

Cofactor

Magnesium By similarity. HAMAP MF_00490

Sequence similarities

Belongs to the ComB family.

Ontologies

Keywords
   LigandMagnesium
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme M biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular function2-phosphosulfolactate phosphatase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490
PRO_1000081391

Sequences

Sequence LengthMass (Da)Tools
A4XFZ6 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: EA77B1234BC459C6

FASTA24227,481
        10         20         30         40         50         60 
MKIITFSHYK EVTDDVLKDS YAVVIDLLRA TSTMIWAISN GAKGIIPVED ISEARLLKRL 

        70         80         90        100        110        120 
DESVLLGGER GGLKIEGFDL DNSPLSYKKE AIFGKTVVMT TTNGTRALKK ASCAKRIFLG 

       130        140        150        160        170        180 
SFINAKKTAE YIMKETLHYN IDTISIVCAG TEEKFTLEDI LCAGYFVDLF IENFPDVFLD 

       190        200        210        220        230        240 
DLSLASHVLY KKFENDPHEI LKYSYHYNHL KKLGFEADLE FCLRKDFVDC VCEFRNLVVE 


KV

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References

[1]"Genome sequence of the thermophilic hydrogen-producing bacterium Caldicellulosiruptor saccharolyticus DSM 8903."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A., VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J., Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M., Kengen S.M.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43494 / DSM 8903.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000679 Genomic DNA. Translation: ABP65831.1.
RefSeqYP_001179022.1. NC_009437.1.

3D structure databases

ProteinModelPortalA4XFZ6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4XFZ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5089237.
GenomeReviewsGene locus Csac_0183 in contig CP000679_GR.
KEGGcsc:Csac_0183.
PATRIC21249756. VBICalSac56748_0217.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2045.
HOGENOMHBG633644.
OMADFICSGY.
ProtClustDBPRK00886.

Family and domain databases

HAMAPMF_00490. ComB.
[Tree]
InterProIPR005238. 2-PSlactate_phosphatase.
IPR022995. Pase_ComB.
[Graphical view]
Gene3DG3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KOK05979.
PfamPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMSSF142823. SSF142823. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOMB_CALS8
AccessionPrimary (citable) accession number: A4XFZ6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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