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Protein

Probable 2-phosphosulfolactate phosphatase

Gene

comB

Organism
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciCSAC351627:GJ17-188-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2-phosphosulfolactate phosphataseUniRule annotation (EC:3.1.3.71UniRule annotation)
Gene namesi
Name:comBUniRule annotation
Ordered Locus Names:Csac_0183
OrganismiCaldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)
Taxonomic identifieri351627 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisCaldicellulosiruptor
Proteomesi
  • UP000000256 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 242242Probable 2-phosphosulfolactate phosphatasePRO_1000081391Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351627.Csac_0183.

Structurei

3D structure databases

ProteinModelPortaliA4XFZ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ComB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.

Sequencei

Sequence statusi: Complete.

A4XFZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIITFSHYK EVTDDVLKDS YAVVIDLLRA TSTMIWAISN GAKGIIPVED
60 70 80 90 100
ISEARLLKRL DESVLLGGER GGLKIEGFDL DNSPLSYKKE AIFGKTVVMT
110 120 130 140 150
TTNGTRALKK ASCAKRIFLG SFINAKKTAE YIMKETLHYN IDTISIVCAG
160 170 180 190 200
TEEKFTLEDI LCAGYFVDLF IENFPDVFLD DLSLASHVLY KKFENDPHEI
210 220 230 240
LKYSYHYNHL KKLGFEADLE FCLRKDFVDC VCEFRNLVVE KV
Length:242
Mass (Da):27,481
Last modified:May 29, 2007 - v1
Checksum:iEA77B1234BC459C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000679 Genomic DNA. Translation: ABP65831.1.
RefSeqiWP_011915796.1. NC_009437.1.

Genome annotation databases

EnsemblBacteriaiABP65831; ABP65831; Csac_0183.
KEGGicsc:Csac_0183.
PATRICi21249756. VBICalSac56748_0217.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000679 Genomic DNA. Translation: ABP65831.1.
RefSeqiWP_011915796.1. NC_009437.1.

3D structure databases

ProteinModelPortaliA4XFZ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351627.Csac_0183.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP65831; ABP65831; Csac_0183.
KEGGicsc:Csac_0183.
PATRICi21249756. VBICalSac56748_0217.

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Enzyme and pathway databases

BioCyciCSAC351627:GJ17-188-MONOMER.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43494 / DSM 8903 / Tp8T 6331.

Entry informationi

Entry nameiCOMB_CALS8
AccessioniPrimary (citable) accession number: A4XFZ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: December 9, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.