ID   A4XFT5_CALS8            Unreviewed;       768 AA.
AC   A4XFT5;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Phosphoprotein phosphatase {ECO:0000313|EMBL:ABP65770.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:ABP65770.1};
GN   OrderedLocusNames=Csac_0117 {ECO:0000313|EMBL:ABP65770.1};
OS   Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS   6331).
OC   Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC   Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX   NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP65770.1, ECO:0000313|Proteomes:UP000000256};
RN   [1] {ECO:0000313|Proteomes:UP000000256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC   {ECO:0000313|Proteomes:UP000000256};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA   VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA   Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA   Kengen S.M.W., Richardson P.;
RT   "Genome sequence of the thermophilic hydrogen-producing bacterium
RT   Caldicellulosiruptor saccharolyticus DSM 8903.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABP65770.1, ECO:0000313|Proteomes:UP000000256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC   {ECO:0000313|Proteomes:UP000000256};
RX   PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA   van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA   Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA   van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA   Kelly R.M., Kengen S.W.;
RT   "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT   saccharolyticus.";
RL   Appl. Environ. Microbiol. 74:6720-6729(2008).
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DR   EMBL; CP000679; ABP65770.1; -; Genomic_DNA.
DR   RefSeq; WP_011915732.1; NC_009437.1.
DR   AlphaFoldDB; A4XFT5; -.
DR   STRING; 351627.Csac_0117; -.
DR   KEGG; csc:Csac_0117; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_017349_0_0_9; -.
DR   OrthoDB; 9763774at2; -.
DR   Proteomes; UP000000256; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR045768; SpoIIE_N.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABP65770.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        66..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          547..755
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   768 AA;  86118 MW;  BFA77AE994513886 CRC64;
     MDKIEVLEFK RQSLKKDQPE GSKTLFFFNA EEYFLLILAF LLGRCDLFST SFFSTSYLSS
     FKKKDYTYYL ASLFSIFGIV SALNRSSVLK YVVSILIITA VNHFFEFNVY IRAIIAAGSV
     FVGGVLSISI FRGMPVEVLY LLLESLFCYC FVLLFERFFD TIGSKKQFSS EQAAITIGVL
     ALSFLGLSST FDSVVDVKKI LFFILLFIIS FGHGMIMSTT MGFVVGLLDS IKEGSSIEMS
     CIFAFAALLA GVMKGFGKIG IVLGGFCGYV ISVFYISSNP TVKLREILIA SALFCIFPLE
     KILINDNNEG EEIQKMIKEK IFGIASVLEN FGDTSYQKVI PIISKDEAKN IIEQTCHKLC
     SGCQNLQTCW QYCYTQTNHN LNEMKNIILK KGKLDENDIK VFKFTCFKSK EFVVVVNGFL
     ESLKYSKLVR NEGVQKESTF KNQIELIKDI VVDAAKMVEK DLKQDRGTAK EIELELCRFG
     YEVEKVDFTL ADDYFQVEIE LKEGFKPPRK KEIEEIVKEI VKCDIEIISE VPKQAGGYTI
     SIIKKPNVII DYAIFSKSKE NVNGDRVCFL QLKDGKFLAC ISDGMGTGKA AADNSFIVID
     ALKKFTSLGF DRKIALKFIN SLLAIKNTEG FASVDIVCID RFNLSCEFLK AGATPTYLKR
     ANRVFEISSN SLPVGIETET QFEYINHKLE KGDMIFMCSD GLLELLGEDG QKELLGYLSS
     HEFLSTQSAT KQIFEWAISN SYGIKDDVTI IVLKVGGASE KKGDEKAS
//